Adrenomedullin (22-52) (human)

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Names

[ CAS No. ]:
159899-65-7

[ Name ]:
Adrenomedullin (22-52) (human)

[Synonym ]:
MFCD00282038
Adrenomedullin (AM) (22-52), human

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅₉H₂₅₂N₄₆O₄₈

[ Molecular Weight ]:
3576.03

[ Storage condition ]:
−20°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Adrenomedullin receptor binding sites in rat brain and peripheral tissues.

Eur. J. Pharmacol. 474 , 165-174, (2003)

The existence of specific adrenomedullin receptor binding sites was investigated using the agonist peptide fragment [125I]human adrenomedullin-(13-52) in rat brain, lung and vas deferens homogenates. ...

Adrenomedullin is anti-apoptotic in osteoblasts through CGRP1 receptors and MEK-ERK pathway.

J. Cell Physiol. 215 , 122-128, (2008)

Adrenomedullin (ADM) has been shown to mediate multifunctional responses in cell culture and animal system such as regulation of growth and apoptosis. ADM stimulates the proliferation of osteoblasts i...

Adrenomedullin antagonist suppresses in vivo growth of human pancreatic cancer cells in SCID mice by suppressing angiogenesis.

Oncogene 22 , 1238-1242, (2003)

Since it is reported that adrenomedullin (AM) upregulated by hypoxia inhibits hypoxic cell death, we examined the effects of AM antagonist (AM C-terminal fragment; AM(22-52)) on the growth of pancreat...

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Adrenomedullin (AM) (13-52), human
Adrenomedullin (human)
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4-(6-Chloro-1H-benzo[d][1,2,3]triazol-1-yl)tetrahydro-2H-thiopyran 1,1-dioxide
5-chloro-1-(2-cyclopropylethyl)-1H-1,2,3-benzotriazole
2-[1-(2-methanesulfonylethyl)-1H-1,2,3-benzotriazol-7-yl]acetic acid
6-chloro-5-fluoro-1-(2-methanesulfonylethyl)-1H-1,2,3-benzotriazole
6-fluoro-1-(2-methanesulfonylethyl)-1H-1,2,3-benzotriazol-5-amine
5-tert-butyl 4-chloromethyl (1S,4S,6R)-7,7-difluoro-2-oxa-5-azabicyclo[4.1.0]heptane-4,5-dicarboxylate
2-tert-butyl 3-chloromethyl (1S,3S,5R)-6,6-difluoro-2-azabicyclo[3.1.0]hexane-2,3-dicarboxylate
2-Tert-butyl 6-chloromethyl 2-azabicyclo[3.1.0]hexane-2,6-dicarboxylate
5-tert-butyl 2-chloromethyl 3-iodo-4H,5H,6H-thieno[2,3-c]pyrrole-2,5-dicarboxylate
Chloromethyl 2-{1-[(tert-butoxy)carbonyl]pyrrolidin-3-yl}-4-(propan-2-yl)-1,3-oxazole-5-carboxylate

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