SB 205384

[ Density]:
1.38g/cm3

[ Boiling Point ]:
565.3ºC at 760 mmHg

[ Molecular Formula ]:
C₁₇H₁₈N₂O₃S

[ Molecular Weight ]:
330.40

[ Flash Point ]:
295.7ºC

[ Exact Mass ]:
330.10400

[ PSA ]:
113.68000

[ LogP ]:
2.79780

[ Vapour Pressure ]:
1.29E-13mmHg at 25°C

[ Index of Refraction ]:
1.691

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Quantitative trait locus analysis identifies Gabra3 as a regulator of behavioral despair in mice.

Mamm. Genome 21(5-6) , 247-57, (2010)

The Tail Suspension Test (TST), which measures behavioral despair, is widely used as an animal model of human depressive disorders and antidepressant efficacy. In order to identify novel genes involve...

Developmental change in GABAA receptor desensitization kinetics and its role in synapse function in rat cortical neurons.

J. Physiol. 522 Pt 1 , 3-17, (2000)

We examined the maturation of GABAA receptor synapses in cortical pyramidal neurons cultured from embryonic rats. The decay kinetics of GABAA receptor-mediated miniature postsynaptic currents (mPSCs) ...

SB-205384: a GABA(A) receptor modulator with novel mechanism of action that shows subunit selectivity.

Br. J. Pharmacol. 123 , 1253-1259, (1998)

1. SB-205384, and its (+) enantiomer (+)-SB-205384 were tested for their modulatory effects on human GABA(A) receptor subunit combinations expressed in Xenopus oocytes by electrophysiological methods....

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