6,7-dihydroxyquinazolin-4(3H)-one

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Names

[ CAS No. ]:
16064-15-6

[ Name ]:
6,7-dihydroxyquinazolin-4(3H)-one

[Synonym ]:
4-Anilinoquinazoline deriv. 53
6,7-dihydroxy-3H-quinazolin-4-one
6,7-dihydroxyquinazolinone

Chemical & Physical Properties

[ Boiling Point ]:
478.6±55.0°C at 760 mmHg

[ Molecular Formula ]:
C8H6N2O3

[ Molecular Weight ]:
178.14500

[ Exact Mass ]:
178.03800

[ PSA ]:
86.47000

[ LogP ]:
0.74660

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 6,7-Dimethoxy-3,4-dihydroquinazoline-4-one
  • 6,7-dimethoxyquinazoline
  • 3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate

DownStream

  • Erlotinib
  • Erlotinib HCl (OSI-744)

Related Compounds

  • 6,7-methylenedioxyquinazoline-4(3H)-one
  • 6,7-DIETHOXYQUINAZOLIN-4(3H)-ONE
  • 6,7-dibromoquinazolin-4(3H)-one
  • 6,7,8-Trimethoxyquinazolin-4(3H)-one
  • 6,7-Difluoro-2-mercaptoquinazolin-4(3H)-one
  • 6,7-DIFLUORO-2-METHYLQUINAZOLIN-4(3H)-ONE
  • Benzyl 2-((5-(benzo[d]thiazole-2-carboxamido)-1,3,4-thiadiazol-2-yl)thio)acetate
  • N-(5-((2,5-difluorobenzyl)thio)-1,3,4-thiadiazol-2-yl)benzo[d]thiazole-2-carboxamide
  • N-(5-((2-oxo-2-(pyrrolidin-1-yl)ethyl)thio)-1,3,4-thiadiazol-2-yl)-1-(thiophen-2-yl)cyclopentanecarboxamide
  • N-[5-({[(2,3-dimethylphenyl)carbamoyl]methyl}sulfanyl)-1,3,4-thiadiazol-2-yl]-1-(thiophen-2-yl)cyclopentane-1-carboxamide
  • N-(5-((2-((2-ethoxyphenyl)amino)-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)-1-(thiophen-2-yl)cyclopentanecarboxamide
  • N-{5-[({[(furan-2-yl)methyl]carbamoyl}methyl)sulfanyl]-1,3,4-thiadiazol-2-yl}-1-(thiophen-2-yl)cyclopentane-1-carboxamide
  • N-(5-((2-oxo-2-(thiazol-2-ylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)-1-(thiophen-2-yl)cyclopentanecarboxamide
  • N-(5-((2-((3-chloro-4-fluorophenyl)amino)-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)-1-(thiophen-2-yl)cyclopentanecarboxamide
  • N-(5-((pyridin-3-ylmethyl)thio)-1,3,4-thiadiazol-2-yl)-1-(thiophen-2-yl)cyclopentanecarboxamide
  • N-(5-((pyridin-2-ylmethyl)thio)-1,3,4-thiadiazol-2-yl)-1-(thiophen-2-yl)cyclopentanecarboxamide
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