MDL 105519

Suppliers

Names

[ Name ]:
MDL 105519

[Synonym ]:
3-[(E)-2-carboxy-2-phenylethenyl]-4,6-dichloro-1H-indole-2-carboxylic acid
3-[(E)-2-Carboxy-2-phenylvinyl]-4,6-dichloro-1H-indole-2-carboxylic acid
1H-Indole-2-carboxylic acid, 3-[(E)-2-carboxy-2-phenylethenyl]-4,6-dichloro-
MFCD00935266

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
601.3±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₈H₁₁Cl₂NO₄

[ Molecular Weight ]:
376.190

[ Flash Point ]:
317.5±31.5 °C

[ Exact Mass ]:
375.006500

[ LogP ]:
5.87

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.764

[ Storage condition ]:
2-8℃

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Pharmacological characterization of MDL 105,519, an NMDA receptor glycine site antagonist.

Eur. J. Pharmacol. 323 , 181-192, (1997)

MDL 105,519, (E)-3-(2-phenyl-2-carboxyethenyl)-4,6-dichloro-1 H-indole-2-carboxylic acid, is a potent and selective inhibitor of [3H]glycine binding to the NMDA receptor. MDL 105,519 inhibits NMDA (N-...

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