4-Amino-7-chloro-3-cinnolinecarboxylic acid

Names

[ CAS No. ]:
161373-47-3

[ Name ]:
4-Amino-7-chloro-3-cinnolinecarboxylic acid

Chemical & Physical Properties

[ Density]:
1.635g/cm3

[ Boiling Point ]:
459.1ºC at 760mmHg

[ Molecular Formula ]:
C9H6ClN3O2

[ Molecular Weight ]:
223.61600

[ Flash Point ]:
231.4ºC

[ Exact Mass ]:
223.01500

[ PSA ]:
89.10000

[ LogP ]:
2.14480

[ Vapour Pressure ]:
3.2E-09mmHg at 25°C

[ Index of Refraction ]:
1.761

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GE3624208
CHEMICAL NAME :
3-Cinnolinecarboxylic acid, 4-amino-7-chloro-, hydrate
CAS REGISTRY NUMBER :
161373-47-3
LAST UPDATED :
199603
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C9-H6-Cl-N3-O2.H2-O
MOLECULAR WEIGHT :
241.65

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
60 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 49,884,1994
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
25 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 49,884,1994

Synthetic Route

Click to get detail synthetic route

Related Compounds

  • 4-amino-7-chloro-6-fluorocinnoline-3-carboxylic acid
  • 4-(benzylideneamino)-7-chloro-6-fluorocinnoline-3-carboxylic acid
  • 6-chloro-1-amino-2-naphthol-4-sulfonic acid
  • 4-aminocinnoline-3-carboxylic acid
  • 7-CHLORO-3-(2,6-DICHLOROPHENYL)-4-IMINO-3,4-DIHYDROPYRIMIDO[4,5-D]PYRIMIDIN-2(1H)-ONE
  • 4-amino-7-chloro-8-methylquinoline-3-carboxylic acid
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 4-Methyl-4-(methylsulfonylmethyl)piperidine;hydrochloride
  • 3-[1,3-Bis(4-bromophenyl)-4-hydroxy-2-oxo-4-imidazolidinyl]-5-chlorobenzonitrile
  • N-(4-butylphenyl)-2-((5,6-dimethyl-7-oxo-7,8-dihydro-[1,2,4]triazolo[4,3-a]pyrimidin-3-yl)thio)acetamide
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(3-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)guanidino)phenyl)propanoic acid
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide