4-(4-Methylpiperazino)aniline

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Names

[ CAS No. ]:
16153-81-4

[ Name ]:
4-(4-Methylpiperazino)aniline

[Synonym ]:
4-(4-Methylpiperazin-1-yl)phenylamine
4-(4-Methylpiperazin-1-yl)aniline
MFCD00172703
1-(4-Aminophenyl)-4-methylpiperazine
4-(4-Methylpiperazino)aniline
Benzenamine, 4-(4-methyl-1-piperazinyl)-
4-(4-Methyl-1-piperazinyl)aniline

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
351.5±37.0 °C at 760 mmHg

[ Melting Point ]:
89 °C

[ Molecular Formula ]:
C11H17N3

[ Molecular Weight ]:
191.273

[ Flash Point ]:
164.0±21.3 °C

[ Exact Mass ]:
191.142242

[ PSA ]:
32.50000

[ LogP ]:
0.52

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.589

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
3259

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2933599090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-METHYL-4-(4-NITROPHENYL)PIPERAZINE
  • 1-Fluoro-4-nitrobenzene
  • methylpiperazine
  • 1-Bromo-4-nitrobenzene
  • 4-Chloronitrobenzene
  • 1-Iodo-4-nitrobenzene

DownStream

  • N-[4-(4-methylpiperazin-1-yl)phenyl]-6-phenylquinolin-4-amine
  • 1-(4-Isothiocyanatophenyl)-4-methylpiperazine
  • Adavosertib (MK-1775)
  • WZ3146
  • 1-[4-(4-Methyl-1-piperazinyl)phenyl]-3-{4-[4-(8-oxa-3-azabicyclo[ 3.2.1]oct-3-yl)-1-(2,2,2-trifluoroethyl)-1H-pyrazolo[3,4-d]pyrimi din-6-yl]phenyl}ure
  • JP1302
  • 1-(4-isocyanatophenyl)-4-methylpiperazine
  • 5-methyl-2-N-[4-(4-methylpiperazin-1-yl)phenyl]pyrimidine-2,4-diamine

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 4-(4-methylpiperazino)aniline
  • 3-Fluoro-4-(4-methylpiperazino)aniline
  • 4-(4-methylpiperazino)aniline hydrochloride
  • 4-(4-Methylpiperazino)-2-(4-methylpiperidino)-aniline
  • 4-(4-METHYLPIPERAZINO)-3-NITROBENZENE-CARBOXYLIC ACID
  • (E)-but-2-enedioic acid,1-(8-fluoro-4,5-dihydrothieno[2,3-b][1]benzothiepin-4-yl)-4-methylpiperazine
  • 2-{1-[(tert-butoxy)carbonyl]-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpiperidin-3-yl}acetic acid
  • 3-{[(Benzyloxy)carbonyl]amino}-3-(3,3-difluorocyclobutyl)butanoic acid
  • (3S)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(3-methyl-1,2-thiazol-5-yl)propanoic acid
  • (3R)-3-(3,5-dimethylthiophen-2-yl)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
  • rac-2-[(1R,5S)-2-{[(benzyloxy)carbonyl]amino}bicyclo[3.1.0]hexan-2-yl]acetic acid
  • (3S)-3-(1-ethyl-1H-1,2,3-triazol-4-yl)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
  • 3-(azetidin-3-yl)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid
  • 2-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2,2-dimethyloxolan-3-yl]acetic acid
  • 2-(1-{[(Benzyloxy)carbonyl]amino}-3-({[(tert-butoxy)carbonyl]amino}methyl)cyclohexyl)acetic acid
  • 2-(1-{[(Benzyloxy)carbonyl]amino}-2-methoxycyclohexyl)acetic acid
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