(S)-N-Glycidylphthalimide

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Names

[ CAS No. ]:
161596-47-0

[ Name ]:
(S)-N-Glycidylphthalimide

[Synonym ]:
(S)-N-(2,3-Epoxypropyl)phthalimide
(S)-(+)-N-(2,3-Epoxypropyl)phthalimide
1H-Isoindole-1,3(2H)-dione, 2-[(2S)-oxiranylmethyl]-
2-[(2S)-oxiran-2ylmethyl]-1H-isoindole-1,3(2H)-dione
2-[(2S)-Oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
(S)-N-Glycidylphthalimide
(S)-2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione
2-[[(2S)-oxiran-2-yl]methyl]isoindole-1,3-dione
MFCD04973350
2-[(2S)-2-Oxiranylmethyl]-1H-isoindole-1,3(2H)-dione
(S)-(+)-Glycidyl Phthalimide
Rivaroxaban Impurity 8

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
347.4±15.0 °C at 760 mmHg

[ Melting Point ]:
102ºC

[ Molecular Formula ]:
C11H9NO3

[ Molecular Weight ]:
203.194

[ Flash Point ]:
163.9±20.4 °C

[ Exact Mass ]:
203.058243

[ PSA ]:
49.91000

[ LogP ]:
1.60

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.649

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H318

[ Precautionary Statements ]:
P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R41

[ Safety Phrases ]:
26-39

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (±)-Glycidol
  • (R)-(-)-Epichlorohydrin
  • Potassium phthalimide
  • (±)-Glycidol
  • (S)-2-(2-acetoxy-3-bromo-propyl)-isoindole-1,3-dione
  • (S)-(+)-Epichlorhydrin
  • (S)-Glycidyl tosylate
  • (S)-2-(3-chloro-2-hydroxypropyl)isoindoline-1,3-dione
  • 1H-Isoindole-1,3(2H)-dione,2-(3-chloro-2-hydroxypropyl)-

DownStream

  • 4-[((2R)-Hydroxy-3-phthalimido)propylamine]phenyl-3-morpholinone
  • (R)-N-[[3-[3-Fluoro-4-[4-morpholinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl]phthalimide
  • N-(3-Phthalimido-2-(R)-hydroxypropyl)-3-fluoro-4-(Morpholinyl)aniline
  • 2-[4-(3,4-Dichloro-benzyl)-morpholin-2-ylmethyl]-isoindole-1,3-dione
  • 2-{[4-(3,4-Dichlorobenzyl)-2-morpholinyl]methyl}-1H-isoindole-1,3 (2H)-dione

Customs

[ HS Code ]: 2925190090

[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Related Compounds

  • (S)-N-isopropyl-N-(2-pyrrolidinylmethyl)amine
  • (-)-(S)-N,N'-Bis-(2-hydroxy-1-aethyl-aethyl)-oxalsaeurediamid
  • (S)-N-(phenylacetyl)-α-phenylglycinonitrile
  • (S)-N-tert-butoxycarbonyl-5-(tert-butyldiphenylsilyloxy)-3-piperidene
  • (-)-(S)-N-(1-dimethylcarbamoyl-1-methylethyl)-2-hydroxy-3-phenylpropanamide
  • (S)-N-(1-hydroxy-3-methylbutan-2-yl)-1(2,5)-pyridinacycloundecaphane-13-carboxamide
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 4-Chloro-7-methoxy-6-(2-morpholin-4-ylethoxy)quinazoline
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 2-[5,5-Dimethyl-4-(1-methylethyl)-1,3-dioxan-2-yl]phenol
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 1-[(Dipropylamino)methyl]-2,3-dihydro-5-methoxy-1H-inden-1-ol
  • 6-Fluoro-3-methylisoindolin-1-one