3-(3,4-Difluorophenyl)propanoic acid

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Names

[ CAS No. ]:
161712-75-0

[ Name ]:
3-(3,4-Difluorophenyl)propanoic acid

[Synonym ]:
Benzenepropanoic acid, 3,4-difluoro-
3-(3,4-Difluorophenyl)propanoic acid
3,4-Difluorohydrocinnamic acid
QV2R CF DF
3,4-Difluorobenzenepropanoic acid
3-(3,4-Difluorophenyl)propionic acid
MFCD00799520

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
277.7±25.0 °C at 760 mmHg

[ Melting Point ]:
49-53 °C(lit.)

[ Molecular Formula ]:
C9H8F2O2

[ Molecular Weight ]:
186.155

[ Flash Point ]:
121.8±23.2 °C

[ Exact Mass ]:
186.049240

[ PSA ]:
37.30000

[ LogP ]:
1.85

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.504

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2916399090

Precursor & DownStream

Precursor

DownStream

  • 5,6-Difluoroindanone
  • 3-(3,4-DIFLUORO-PHENYL)-PROPIONIC ACID ETHYL ESTER
  • 6,7-difluoro-2,3-dihydro-1H-inden-1-one

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Multi-target-directed coumarin derivatives: hAChE and BACE1 inhibitors as potential anti-Alzheimer compounds.

Bioorg. Med. Chem. Lett. 18(1) , 423-6, (2008)

The complex etiology of Alzheimer's disease (AD) prompts scientists to develop multifunctional compounds to combat causes and symptoms of such neurodegeneration. To this aim we designed, synthesized, ...


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Related Compounds

  • 2-amino-3-(3,4-difluorophenyl)propanoic acid
  • 3-amino-3-(3,4-difluorophenyl)propanoic acid
  • (R)-2-Amino-3-(3,4-difluorophenyl)propanoic acid
  • (S)-2-Amino-3-(3,4-difluorophenyl)propanoic acid
  • 2-acetamido-3-(3,4-difluorophenyl)propanoic acid
  • 2-(aminomethyl)-3-(3,4-difluorophenyl)propanoic acid