6α-Methyl Hydrocortisone

Names

[ CAS No. ]:
1625-39-4

[ Name ]:
6α-Methyl Hydrocortisone

[Synonym ]:
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one

Chemical & Physical Properties

[ Density]:
1.26g/cm3

[ Boiling Point ]:
568.2ºC at 760mmHg

[ Molecular Formula ]:
C22H32O5

[ Molecular Weight ]:
376.48600

[ Flash Point ]:
311.5ºC

[ Exact Mass ]:
376.22500

[ PSA ]:
94.83000

[ LogP ]:
2.02760

[ Vapour Pressure ]:
2.83E-15mmHg at 25°C

[ Index of Refraction ]:
1.586

Precursor & DownStream

Precursor

  • Methylprednisolone
  • 11beta,21-dihydroxy-6alpha-methylpregna-4,17(20)-dien-3-one 21-acetate
  • [2-(11,17-dihydroxy-6,10,13-trimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl] acetate
  • 3,20-Bis-ethylendioxy-6β-methyl-pregnan-5α,11β,17α,21-tetrol
  • 3,3;20,20-bis-ethanediyldioxy-5,6α-epoxy-5α-pregnane-11β,17,21-triol

DownStream

  • [2-(11,17-dihydroxy-6,10,13-trimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl] acetate
  • (8S,9S,10R,11S,13S,14S,17R)-17-(2-fluoroacetyl)-11,17-dihydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one

Related Compounds

  • 6α-Methyl-17-(trimethylsiloxy)pregn-4-ene-3,20-dione bis(O-methyl oxime)
  • 6α-Methyl-17-(trimethylsiloxy)pregn-4-ene-3,20-dione
  • 6α-Methyl-17,21-bis[(trimethylsilyl)oxy]pregn-4-ene-3,20-dione bis(O-methyl oxime)
  • 6α-methyl-9,11β-epoxy-17α-hydroxy-pregna-1,4-diene-3,20-dione
  • 6α-Methyl-hydrocortison
  • 4-[2-[(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-6,10,13-trimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethoxy]-4-oxobutanoic acid