Ezetimibe

Suppliers

Names

[ CAS No. ]:
163222-33-1

[ Name ]:
Ezetimibe

[Synonym ]:
Ezetimide
Zetia
EzitiMibeEzetiMibeC24H21F2N03
Ezetrol
(3R,4S)-1-(4-fluorophényl)-3-[(3S)-3-(4-fluorophényl)-3-hydroxypropyl]-4-(4-hydroxyphényl)azétidin-2-one
Int
(3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone
ezetimibe
EzetiMib
(3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one
(3R,4S)-1-(4-Fluorphenyl)-3-[(3S)-3-(4-fluorphenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-on
MFCD00937872
2-Azetidinone, 1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-, (3R,4S)-

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
654.9±55.0 °C at 760 mmHg

[ Melting Point ]:
164-166℃

[ Molecular Formula ]:
C24H21F2NO3

[ Molecular Weight ]:
409.425

[ Flash Point ]:
349.9±31.5 °C

[ Exact Mass ]:
409.148956

[ PSA ]:
60.77000

[ LogP ]:
3.26

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.624

[ Storage condition ]:
-20?C Freezer

Safety Information

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Ezetimibe Ketone
  • 4'-O-Benzyloxy Ezetimibe
  • (3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]azetidin-2-one
  • (3R,4S)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-(trityloxy)phenyl)azetidin-2-one
  • 3-{2-[3-(fluorophenyl)-3-(trimethyl silyloxy)-propyl]-3-(4-fluoro phenyl amino)-3-(4-trimethyl silyloxy phenyl)-1-oxo-propyl}-4-(S)-phenyl oxazolidin-2-one
  • 2-​Azetidinone, 4-​[4-​[[(1,​1-​dimethylethyl)​dimethylsilyl]​oxy]​phenyl]​-​1-​(4-​fluorophenyl)​-​3-​[(3S)​-​3-​(4-​fluorophenyl)​-​3-​hydroxypropyl]​-​, (3R,​4S)​
  • (3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]azetidin-2-one

DownStream

  • [4-[(2S,3R)-3-[(3R)-3-acetyloxy-3-(4-fluorophenyl)propyl]-1-(4-fluorophenyl)-4-oxoazetidin-2-yl]phenyl] acetate

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • ezetimibe
  • Ezetimibe D4
  • Ezetimibe-d4
  • (R)-Ezetimibe
  • Ezetimibe Diol
  • Ezetimibe-13C6
  • {5-[(Dipropylamino)methyl]pyridin-3-yl}methanamine
  • 1'-Propyl-4-azaspiro[bicyclo[2.2.2]octane-2,2'-pyrrolidine]-3'-amine
  • (7R,9S)-7,9-dimethyl-1-propyl-8-oxa-1-azaspiro[4.5]decan-4-amine
  • 1-Bromo-2,5-dichloro-3-ethoxybenzene
  • 1-[3-Amino-4-(trifluoromethyl)pyrrolidin-1-yl]propan-1-one
  • (4-Cyclobutanecarbonyl-2-propylmorpholin-2-yl)methanamine
  • 2-(aminomethyl)-2-methyl-N-(3-methylbutan-2-yl)morpholine-4-carboxamide
  • 2-(aminomethyl)-2-ethyl-N-(3-methylbutan-2-yl)morpholine-4-carboxamide
  • 2-(aminomethyl)-N-(2-methylbutan-2-yl)-2-propylmorpholine-4-carboxamide
  • 3-(2,3-Dichlorophenyl)-2,6-difluoroaniline
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.