Malaoxon
Suppliers
Names
[ CAS No. ]:
1634-78-2
[ Name ]:
Malaoxon
[Synonym ]:
diethyl 2-[(dimethoxyphosphoryl)thio]succinate
Malathion impurity B
Liromat
Diethyl-2-[(dimethoxyphosphoryl)sulfanyl]butandioat
Malathion-O-analog
dimethoxyphosphorylsulfanyl-succinic acid diethyl ester
Maloxon
rac-malaoxon
diethyl 2-[(dimethoxyphosphoryl)sulfanyl]butanedioate
Diethyl 2-[(dimethoxyphosphoryl)sulfanyl]succinate
Butanedioic acid, 2-[(dimethoxyphosphinyl)thio]-, diethyl ester
Dimethoxyphosphorylmercapto-bernsteinsaeure-diaethylester
MFCD00055461
Butanedioic acid, [(dimethoxyphosphinyl)thio]-, diethyl ester
Malaoxone
Oxycarbophos
Carbethoxy malaoxon
Malaoxon
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
376.0±52.0 °C at 760 mmHg
[ Melting Point ]:
<20℃
[ Molecular Formula ]:
C10H19O7PS
[ Molecular Weight ]:
314.292
[ Flash Point ]:
181.2±30.7 °C
[ Exact Mass ]:
314.058899
[ PSA ]:
123.24000
[ LogP ]:
2.07
[ Appearance of Characters ]:
liquid
[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C
[ Index of Refraction ]:
1.470
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- WM8410000
- CHEMICAL NAME :
- Succinic acid, mercapto-, diethyl ester, S-ester with O,O-dimethylphosphorothioate
- CAS REGISTRY NUMBER :
- 1634-78-2
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 12
- MOLECULAR FORMULA :
- C10-H19-O7-P-S
- MOLECULAR WEIGHT :
- 314.32
- WISWESSER LINE NOTATION :
- 2OV1YVO2&SPO&O1&O1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 158 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 17500 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 215 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 75 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 119 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - changes in structure or function of salivary glands
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 8200 ug/kg
- SEX/DURATION :
- female 18 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - other effects Reproductive - Specific Developmental Abnormalities - Central Nervous System
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 100 umol/L
- REFERENCE :
- JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 8,939,1981
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301-H310
[ Precautionary Statements ]:
Missing Phrase - N15.00950417-P262-P280-P302 + P352 + P310-P361 + P364
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
F,Xn,N,T
[ Risk Phrases ]:
11-38-50/53-65-67-24/25
[ Safety Phrases ]:
60-61-62-45-36/37/39-46-37-24
[ RIDADR ]:
UN 3018
[ RTECS ]:
WM8410000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
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This work presents the development of bioassays and biosensors for the detection of insecticides widely used in the treatment of olive trees. The systems are based on the covalent immobilisation of ac...
Sci. Total Environ. 488-489 , 208-19, (2014)
The purpose of this study was to evaluate the potential impact of the pesticides detected in the Alqueva reservoir (Guadiana Basin, South Iberian Peninsula) on the aquatic organisms belonging to this ...
Biol. Cell 13 , 343-63, (2008)
We have evaluated the potential of plasma albumin to provide a sensitive biomarker of exposure to commonly used organophosphorus pesticides in order to complement the widely used measure of acetylchol...