5-Chloro-2-nitroaniline

Suppliers

Names

[ Name ]:
5-Chloro-2-nitroaniline

[Synonym ]:
Aniline, 5-chloro-2-nitro-
Benzenamine, 5-chloro-2-nitro-
3-amino-4-nitro-chlorobenzene
5-chlor-2-nitroanilin
2-Amino-4-chloro-nitrobenzene
5-chloro-2-nitro-phenylamine
4-chloro-2-amino-nitrobenzene
5-Chloro-2-nitrobenzenamine
MFCD00007776
2-Amino-4-chloronitrobenzene
EINECS 216-661-5
5-Chloro-2-nitroaniline
Benzenamine,5-chloro-2-nitro
5-chloro-2-nitro aniline
3-Chloro-6-nitroaniline
5-Chloro-2-nitrobenzeneamine
2-Nitro-5-chloroaniline
2-amino-4-chloro-1-nitrobenzene

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
323.4±22.0 °C at 760 mmHg

[ Melting Point ]:
125-129 °C (dec.)(lit.)

[ Molecular Formula ]:
C₆H₅ClN₂O₂

[ Molecular Weight ]:
172.569

[ Flash Point ]:
149.4±22.3 °C

[ Exact Mass ]:
172.003952

[ PSA ]:
71.84000

[ LogP ]:
2.76

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.646

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06, GHS08, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H300 + H310 + H330-H373-H411

[ Precautionary Statements ]:
P260-P264-P273-P280-P284-P301 + P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
T+,N,T

[ Risk Phrases ]:
R26/27/28;R33;R51/53

[ Safety Phrases ]:
S28-S36/37-S45-S61-S28A

[ RIDADR ]:
UN 2237 6.1/PG 3

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
29214210

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

4-Chloronitrobenzene
Acetamide, N-(5-chloro-2-nitrophenyl)-
2,4-Dichloronitrobenzene
4-Chloro-2-fluoronitrobenzene
2-[2-[(E)-2-[4-(dimethylamino)phenyl]ethenyl]-6-methylpyran-4-ylidene]propanedinitrile
Methanol
Sodium Methylate
1-Chloro-3,4-dinitrobenzene
3-Chloroaniline
Acetamide,N-(3-chlorophenyl)-

DownStream

1-[4-(3-amino-4-nitrophenyl)piperazin-1-yl]ethanone
5-Chloro-2-nitro-N-methylaniline
5-phenylthio-1,2-diamino benzene
2-NITRO-5-(PROPYLTHIO)ANILINE
Acetamide, N-(5-chloro-2-nitrophenyl)-
Dovitinib (TKI-258, CHIR-258)
2-nitro-5-(phenylthio)aniline
1H-Benzimidazole, 6-chloro-2-(trichloromethyl)-
4-chloro-3-nitrobenzene-1,2-diamine
2-[(4-nitro-2,1,3-benzoxadiazol-7-yl)amino]acetic acid

Customs

[ HS Code ]: 2921420090

[ Summary ]:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Piperazine derivatives of benzimidazole as potential anthelmintics. Part 1: Synthesis and activity of methyl-5-(4-substituted piperazin-1-yl)benzimidazole-2-carbamates.

Pharmazie 44(9) , 606-7, (1989)

A series of 5-(4-substituted piperazin-1-yl)-2-nitroanilines (4) and 5-(4-substituted piperazin-1-yl)benzimidazole-2-carbamates (6) has been synthesized starting from 5-chloro-2-nitroaniline (3) and N...

Traceless solid-phase synthesis of 5-benzoylbenzimidazoles.

Can. J. Chem. 79(11) , 1556-1561, (2001)