4-Pregnen-6-beta,17,21-triol-3,11,20-trione

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Names

[ CAS No. ]:
16355-28-5

[ Name ]:
4-Pregnen-6-beta,17,21-triol-3,11,20-trione

[Synonym ]:
4-PREGNEN-6BETA,17ALPHA,21-TRIOL-3,11,20-TRIONE
6B-hydroxycortisone approx.

Chemical & Physical Properties

[ Density]:
1.35g/cm3

[ Boiling Point ]:
615.1ºC at 760mmHg

[ Molecular Formula ]:
C21H28O6

[ Molecular Weight ]:
376.44300

[ Flash Point ]:
339.8ºC

[ Exact Mass ]:
376.18900

[ PSA ]:
111.90000

[ LogP ]:
0.96060

[ Vapour Pressure ]:
1.06E-17mmHg at 25°C

[ Index of Refraction ]:
1.603

Synthetic Route

Precursor & DownStream

Precursor

  • Cortisone acetate
  • 2-((5R,10R,13S,17R)-6-acetoxy-5,17-dihydroxy-10,13-dimethyl-3,11-dioxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate

DownStream

  • Pregn-4-ene-3,11,20-trione,6b,17,21-trihydroxy-, 21-acetate(7CI,8CI)

Related Compounds

  • Pregna-1,4-diene-3,11,20-trione, 6,17,21-trihydroxy-, (6β)
  • 6,17,21-Tris[(trimethylsilyl)oxy]pregn-4-ene-3,11,20-trione 3,20-bis(O-methyloxime)
  • Cortisone-2,2,4,6,6,9,12,12-d₈
  • Cortisone-d7
  • 4-Pregnene-17,21-diol-3,11,20-trione 21-sulphate,sodium salt
  • 17,21-[(Cyclohexylboranediyl)bisoxy]pregn-4-ene-3,11,20-trione
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • O-[1-(3-fluoropyridin-4-yl)ethyl]hydroxylamine
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-[5-ethyl-1-(oxolan-2-ylmethyl)-1H-1,2,3-triazol-4-yl]ethan-1-amine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 1-[(tert-butoxy)carbonyl]-3-{[(2R)-1-cyclohexylpropan-2-yl]({[(9H-fluoren-9-yl)methoxy]carbonyl})amino}azetidine-3-carboxylic acid
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • tert-butyl N-[5-(2-azidoethyl)pyrimidin-2-yl]carbamate