N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline

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Names

[ CAS No. ]:
16357-59-8

[ Name ]:
N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline

[Synonym ]:
1-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline
2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline
1(2H)-Quinolinecarboxylic acid, 2-ethoxy-, ethyl ester
Ethyl 1,2-dihydro-2-ethoxyquinoline-1-carboxylate
2-Ethoxy-1(2H)-quinolinecarboxylic Acid Ethyl Ester
EEDQ
EINECS 240-418-2
Ethyl-2-ethoxychinolin-1(2H)-carboxylat
ethyl 2-ethoxy-2H-quinoline-1-carboxylate
2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline (EEDQ)
ethyl 2-ethoxyquinoline-1(2H)-carboxylate
MFCD00006703
Ethyl 2-ethoxy-1(2H)-quinolinecarboxylate

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
355.9±42.0 °C at 760 mmHg

[ Melting Point ]:
62-67 °C(lit.)

[ Molecular Formula ]:
C14H17NO3

[ Molecular Weight ]:
247.290

[ Flash Point ]:
169.0±27.9 °C

[ Exact Mass ]:
247.120850

[ PSA ]:
38.77000

[ LogP ]:
2.98

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.565

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
insoluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VB2010000
CHEMICAL NAME :
1(2H)-Quinolinecarboxylic acid, 2-ethoxy-, ethyl ester
CAS REGISTRY NUMBER :
16357-59-8
BEILSTEIN REFERENCE NO. :
0533048
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C14-H17-N-O3
MOLECULAR WEIGHT :
247.32
WISWESSER LINE NOTATION :
T66 BN CHJ BVO2 CO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
32 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 14,49,1971

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S22-S24/25-S36/37/39-S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
VB2010000

[ HS Code ]:
29334990

Precursor & DownStream

Precursor

DownStream

  • leucoline
  • Ethanol
  • Methyl isonicotinate 1-oxide
  • Ethyl 2-thiazolecarbamate

Customs

[ HS Code ]: 2933499090

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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