4-Amino-5-pyrimidinecarbonitrile

Names

[ CAS No. ]:
16357-69-0

[ Name ]:
4-Amino-5-pyrimidinecarbonitrile

[Synonym ]:
4-Amino-5-pyrimidinecarbonitrile
MFCD00054552
4-Aminopyrimidine-5-carbonitrile

Chemical & Physical Properties

[ Density]:
1.34 g/cm3

[ Boiling Point ]:
355.8ºC at 760 mmHg

[ Melting Point ]:
251-255 °C(lit.)

[ Molecular Formula ]:
C₅H₄N₄

[ Molecular Weight ]:
120.11200

[ Flash Point ]:
169ºC

[ Exact Mass ]:
120.04400

[ PSA ]:
75.59000

[ LogP ]:
0.51168

[ Vapour Pressure ]:
3.05E-05mmHg at 25°C

[ Index of Refraction ]:
1.6

MSDS

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H312-H315-H317-H318-H332-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S26-S36/37/39

[ RIDADR ]:
UN3439

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2933599090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Three-component process for the synthesis of 4-amino-5-pyrimidinecarbonitriles under thermal aqueous conditions or microwave irradiation. Sheibani H, et al.

ARKIVOC 2 , 115-123, (2008)

Synthesis, antimicrobial activity, structural and spectral characterization and DFT calculations of Co (II), Ni (II), Cu (II) and Pd (II) complexes of 4-amino-5-pyrimidinecarbonitrile. Mohamed TA, et al.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 135 , 417-427, (2015)

Synthesis of quinazoline-2,4(1H,3H)-diones from carbon dioxide and 2-aminobenzonitriles using [Bmim]OH as a homogeneous recyclable catalyst. Patil YP, et al.

Catal. Today 148(3) , 355-360, (2009)

4-Amino-5-cyano-6-ethoxy-N-[4-(methylsulfonyl)benzyl]-2-pyridinec arboxamide
4-Amino-2-ethynyl-5-pyrimidinecarbonitrile
4-AMINO-2-(ETHYLTHIO)-5-PYRIMIDINECARBONITRILE
4-Amino-2-methyl-5-pyrimidinecarbonitrile
4-AMINO-2-(DIMETHYLAMINO)-5-PYRIMIDINECARBONITRILE
4-Amino-2-bromo-5-pyrimidinecarbonitrile
5-{[3-(2,4-dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}-2-(4-ethylphenyl)-4H,5H-pyrazolo[1,5-a]pyrazin-4-one
2-(4-ethylphenyl)-5-((3-(pyridin-2-yl)-1,2,4-oxadiazol-5-yl)methyl)pyrazolo[1,5-a]pyrazin-4(5H)-one
2-(4-ethylphenyl)-5-({3-[4-(methylsulfanyl)phenyl]-1,2,4-oxadiazol-5-yl}methyl)-4H,5H-pyrazolo[1,5-a]pyrazin-4-one
3-[(4-chlorophenyl)methyl]-6-{[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one
6-{[3-(2H-1,3-benzodioxol-5-yl)-1,2,4-oxadiazol-5-yl]methyl}-3-[(4-chlorophenyl)methyl]-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one
3-(4-chlorobenzyl)-6-{[3-(3,5-dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}-3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one
2-{[2-(2-butoxyphenyl)pyrazolo[1,5-a]pyrazin-4-yl]sulfanyl}-N-(2-methylphenyl)acetamide
2-{[2-(2-butoxyphenyl)pyrazolo[1,5-a]pyrazin-4-yl]sulfanyl}-N-(4-methylphenyl)acetamide
2-{[2-(2-butoxyphenyl)pyrazolo[1,5-a]pyrazin-4-yl]sulfanyl}-N-(3-chlorophenyl)acetamide
2-{[2-(2-butoxyphenyl)pyrazolo[1,5-a]pyrazin-4-yl]sulfanyl}-N-(4-chlorophenyl)acetamide

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