tolylboronic acid

Suppliers

Names

[ Name ]:
tolylboronic acid

[Synonym ]:
2-Methylbenzeneboronic acid
(2-Methylphenyl)boronic acid
2-Tolylboronic acid
Boronic acid, B-(2-methylphenyl)-
2-methylphenylboronic acid
MFCD00093526
o-Tolylboronic acid
tolylboronic acid

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
283.4±33.0 °C at 760 mmHg

[ Melting Point ]:
162-164 °C(lit.)

[ Molecular Formula ]:
C₇H₉BO₂

[ Molecular Weight ]:
135.96

[ Flash Point ]:
125.2±25.4 °C

[ Exact Mass ]:
136.069565

[ PSA ]:
40.46000

[ LogP ]:
2.05

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.528

[ Storage condition ]:
0-6°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
ED7777777

[ HS Code ]:
2931900090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

2-Bromotoluene
o-Tolyl Trifluoromethanesulfonate
4-Iodotoluene
2-Chlorotoluene
4,4,5,5-Tetramethyl-2-(2-methylphenyl)-1,3,2-dioxaborolane
o-tolylmagnesium bromide
Trimethyl borate
Tert-Butyllithium
N,N-diisopropylboranamine
Water

DownStream

2-ETHOXYCHROMAN
4-BROMO-2'-METHYLBENZOPHENONE
1-bromo-4-(2-methylphenyl)benzene
(4-chlorophenyl)-(2-methylphenyl)methanone
2'-METHYL-[1,1'-BIPHENYL]-4-CARBOXYLIC ACID
2-Formylphenylboronic acid
(2-Bromomethylphenyl)boronic acid pinacol ester
Ethyl (2-methylphenyl)acetate
3-(2-methylphenyl)-2H-furan-5-one
Formamide,N-(2-methylphenyl)-

Customs

[ HS Code ]: 2931900090

[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

Articles

Ruthenium(0)-catalyzed sp3 C-H bond arylation of benzylic amines using arylboronates.

Org. Lett. 7th ed., 14 , 1930-1933, (2012)

A Ru-catalyzed direct arylation of benzylic sp(3) carbons of acyclic amines with arylboronates is reported. This highly regioselective and efficient transformation can be performed with various combin...

Design and synthesis of active site inhibitors of the human farnesyl pyrophosphate synthase: apoptosis and inhibition of ERK phosphorylation in multiple myeloma cells.

J. Med. Chem. 7th ed., 55 , 3201-3215, (2012)

Human farnesyl pyrophosphate synthase (hFPPS) controls intracellular levels of FPP and post-translational prenylation of small GTPase proteins, which are essential for cell signaling and cell prolifer...

Efficient chiral monophosphorus ligands for asymmetric Suzuki-Miyaura coupling reactions.

Org. Lett. 9th ed., 14 , 2258-2261, (2012)

A series of novel P-chiral monophosphorus ligands exhibit efficiency in asymmetric Suzuki-Miyaura coupling reactions, enabling the construction of an array of chiral biaryl products in high yields and...

m-Tolylboronic acid
m-Tolylboronic acid
4-Tolylboronic acid
3-Nitro-p-tolylboronic Acid
3-Amino-p-tolylboronic Acid
3-Nitro-p-tolylboronic Acid
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Bromo-5-propylfuran
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
tert-Butyl-DL-alanine
4-(6-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)pyridin-2-YL)morpholine