2,2,2-Trifluoroethanesulfonyl chloride

Names

[ Name ]:
2,2,2-Trifluoroethanesulfonyl chloride

[Synonym ]:
EINECS 216-713-7
MFCD00007458
2,2,2-Trifluoroethanesulfonyl chloride
Ethanesulfonyl chloride, 2,2,2-trifluoro-

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
147.5±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂H₂ClF₃O₂S

[ Molecular Weight ]:
182.549

[ Flash Point ]:
72.2±0.0 °C

[ Exact Mass ]:
181.941605

[ PSA ]:
42.52000

[ LogP ]:
1.54

[ Vapour Pressure ]:
5.6±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.376

[ Storage condition ]:
2-8°C

MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C: Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 3265 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2904909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

tert-butyl(2,2,2-trifluoroethyl)sulfane
benzyl 2,2,2-trifluoroethyl sulfide
2,2,2-Trifluoroethyl thiocyanate
2,2,2-TRIFLUOROETHANETHIOL
2,2,2-trifluoroethanesulfonyl fluoride

DownStream

2,2,2-trifluoroethanesulfonic acid
4-[2-(1-Pipiridine)ethoxybenzoic acid hydrochloride
2,2,2-Trifluoroethanesulfonamide

Customs

[ HS Code ]: 2904909090

[ Summary ]:
HS:2904909090 sulphonated, nitrated or nitrosated derivatives of hydrocarbons, whether or not halogenated VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Tresyl-based conjugation of protein antigen to lipid nanoparticles increases antigen immunogenicity

Int. J. Pharm. 401(1-2) , 87-92, (2010)

The present studies were aimed at investigating the engineering of NPs with protein-conjugated-surfactant at their surface. In order to increase the immunogenicity of a protein antigen, Brij 78 was fu...

Compared stability of Sepharose-based immunoadsorbents prepared by various activation methods.

J. Chromatogr. A. 584(1) , 17-22, (1992)

During the use of chromatographic supports for the purification of proteins or the selective removal of substances by immunoaffinity, leakage of the antibodies immobilized on the matrix is systematica...

Multifunctional commercially pure titanium for the improvement of bone integration: Multiscale topography, wettability, corrosion resistance and biological functionalization.

Mater. Sci. Eng. C. Mater. Biol. Appl. 60 , 384-93, (2015)

The objects of this research are commercially pure titanium surfaces, with multifunctional behavior, obtained through a chemical treatment and biological functionalization. The explored surfaces are o...

1-chloro-2,2,2-trifluoroethanesulfonyl chloride
2,2,2-trichloroethanethioyl chloride
2,2,2-trifluoroethanaminium chloride
2-(2,2-diphenylacetyl)oxybutyl-diethylazanium,chloride
2-(2,2,2-trifluoroethylsulfanyl)acetyl chloride
2,2,2-trifluoro-N-hydroxyethanimidoyl chloride
1-{3-[(Oxolan-3-yl)methoxy]azetidin-1-yl}-2-phenoxypropan-1-one
3-(2-(3-((1H-1,2,4-triazol-1-yl)methyl)azetidin-1-yl)-2-oxoethyl)-6-cyclopropylpyrimidin-4(3H)-one
N-(3-methoxyphenyl)-1,4-oxazepane-4-carboxamide
5-Chloro-6-(4-(((6-cyclopropylpyrimidin-4-yl)oxy)methyl)piperidin-1-yl)nicotinonitrile
1-((3-Fluorophenyl)sulfonyl)-4-(tetrahydrothiophen-3-yl)-1,4-diazepane
1-((3,4-Dimethylphenyl)sulfonyl)-4-(tetrahydrofuran-3-yl)-1,4-diazepane
N-{[3-(2-hydroxyethoxy)thiolan-3-yl]methyl}-2,6-dimethoxybenzamide
N-[(6-cyclopropylpyridin-3-yl)methyl]-4-phenyloxane-4-carboxamide
(1-methyl-1H-indol-3-yl)(1,4-oxazepan-4-yl)methanone
6-methyl-2-((1-(2-phenylacetyl)piperidin-4-yl)methyl)pyridazin-3(2H)-one

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