mecoprop-p

Names

[ Name ]:
mecoprop-p

[Synonym ]:
Mecoprop-P
d-Mecoprop
(2R)-2-(4-chloro-2-methylphenoxy)propanoic acid
(R)-2-(4-chloro-o-tolyloxy)propionic acid
2M-4XP
Duplosan KV
mecoprop-P
Mecoprop,D

Chemical & Physical Properties

[ Density]:
1.265g/cm3

[ Boiling Point ]:
331.9ºC at 760mmHg

[ Molecular Formula ]:
C₁₀H₁₁ClO₃

[ Molecular Weight ]:
214.64600

[ Flash Point ]:
154.5ºC

[ Exact Mass ]:
214.04000

[ PSA ]:
46.53000

[ LogP ]:
2.50030

[ Index of Refraction ]:
1.5390 (estimate)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UE9755000

CHEMICAL NAME :: Propionic acid, 2-((4-chloro-o-tolyl)oxy)-, (+)-

CAS REGISTRY NUMBER :: 16484-77-8

LAST UPDATED :: 199206

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C10-H11-Cl-O3

MOLECULAR WEIGHT :: 214.66

WISWESSER LINE NOTATION :: QVY1&OR DG B1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1050 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C193,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C193,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 680 mg/kg

TOXIC EFFECTS :: Kidney, Ureter, Bladder - other changes Blood - other changes

REFERENCE :: ZDBEA9 Zdravookhranenie Belorussii. Public Health Service of White Russia. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1955- Volume(issue)/page/year: 23(11),83,1977

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Bird - quail

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C193,1991 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 5 gm/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue)

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 33,1479,1983

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 3 gm/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 33,1479,1983

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 4 gm/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 33,1479,1983

Safety Information

[ Symbol ]:

GHS05, GHS07, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H318-H411

[ Precautionary Statements ]:
P273-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;N: Dangerous for the environment;

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
13-26-37/39-46-61

[ RIDADR ]:
UN3077 9/PG 3

[ RTECS ]:
UE9755000

[ HS Code ]:
2918990022

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

mecoprop methyl ester
(R)-Ethyl 2-(4-chloro-2-methylphenoxy)propanoate
Methyl 2-(2-chloro-6-methylphenoxy)propanoate
4-Chloro-2-methylphenol
Mecoprop
(R)-(+)-1-(4-Pyridyl)ethanol
2-(4-Chlor-2-methylphenoxy)propionsaeureanhydrid

DownStream

Customs

[ HS Code ]: 2918990022

[ Summary ]:
2918990022 2-(4-chloro-2-methylphenoxy)acetic acid。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%

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