1,2-Dichloro-1,1-difluoroethane

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Names

[ CAS No. ]:
1649-08-7

[ Name ]:
1,2-Dichloro-1,1-difluoroethane

[Synonym ]:
1,2-DICHLORO-1,1-DIFLUOROETHANE
EINECS 216-714-2
MFCD00042125
HCFC-132b

Chemical & Physical Properties

[ Density]:
1.416 g/cm3

[ Boiling Point ]:
46-47ºC

[ Melting Point ]:
-101.2ºC

[ Molecular Formula ]:
C2H2Cl2F2

[ Molecular Weight ]:
134.94000

[ Exact Mass ]:
133.95000

[ LogP ]:
2.05680

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KI0950000
CHEMICAL NAME :
Ethane, 1,2-dichloro-1,1-difluoro-
CAS REGISTRY NUMBER :
1649-08-7
BEILSTEIN REFERENCE NO. :
1733206
LAST UPDATED :
199712
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C2-H2-Cl2-F2
MOLECULAR WEIGHT :
134.94
WISWESSER LINE NOTATION :
GXFF1G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0530580 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
25 gm/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0530581
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
20000 ppm/4H
TOXIC EFFECTS :
Behavioral - general anesthetic Behavioral - somnolence (general depressed activity) Liver - other changes
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 19,1,1971 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2000 ppm/6H/13W-I
TOXIC EFFECTS :
Liver - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0530614 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
DOSE :
2000 ppm/6H
SEX/DURATION :
male 14 week(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
REFERENCE :
EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0587-0676

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R59

[ Safety Phrases ]:
23-36/37/39

[ RIDADR ]:
UN 3082

[ HS Code ]:
2903791090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • f 142b
  • f 133a
  • tetrachloroethane
  • Trichloroethylene
  • 1,1,2-trichloro-1-fluoroethane
  • 1,1-Dichloro-1-fluoroethane
  • Difluoroethane
  • 2-Chloro-1,1-difluoroethene
  • 1,1-difluoroethylene
  • Dichloromethane

DownStream

  • 1,1,1,2-Tetrafluoroethane
  • f 133a
  • 2-Chloro-1,1-difluoroethene
  • (Z)-1,2-Dichloro-1-fluoroethene
  • Trichloroethylene
  • 1,2-dichlorofluoroethylene
  • 1,2,2-Trichloro-1,1-difluoroethane
  • Tetrafluoroethylene
  • fluoroethyne

Customs

[ HS Code ]: 2903791090

[ Summary ]:
2903791090 halogenated derivatives of methane, ethane or propane (hcfcs)only with fluorine and chlorine。supervision conditions:14xy(import license,export license,export license,export license)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0%

Related Compounds

  • 1,2-Dichloro-1,1,3,3,3-pentafluoropropane
  • 1,2-Dichloro(1,1-dimethylethyl)benzene
  • 1,2-dichloro-1,1,2,2-tetranitroethane
  • 1,2-dichloro-1,1,2,2-tetrakis-(4-chloro-phenyl)-ethane
  • 1,2-dichloro-1,1,2,4,4-pentafluoro-4-iodobutane
  • 1,2-dichloro-1,1,2,3,3-pentafluoropropane