Tryptoline

Suppliers

Names

[ Name ]:
Tryptoline

[Synonym ]:
2,3,4,9-Tetrahydro-1H-β-carboline
Tetrahydro-b-carboline
Tetrahydro-β-carboline
1,2,3,4-Tetrahydro-b-carboline
2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole
MFCD00004954
1,2,3,4-Tetrahydro-9H-Pyrido[3,4-B]Indole
Tetrahydro-beta-carboline
Triptoline
Tryptoline

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
351.6±32.0 °C at 760 mmHg

[ Melting Point ]:
206-208 °C(lit.)

[ Molecular Formula ]:
C₁₁H₁₂N₂

[ Molecular Weight ]:
172.226

[ Flash Point ]:
166.5±25.1 °C

[ Exact Mass ]:
172.100052

[ PSA ]:
27.82000

[ LogP ]:
1.33

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.670

[ Storage condition ]:
Refrigerator

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

tryptamine
Glyoxylic acid
Formaldehyde
2-benzyl-7-chloro-1,2,3,4-tetrahydro-1H-β-carboline
3-methyl-1,3-oxazolidine
3-Phenyloxazolidine
2H-1,3-Oxazine,tetrahydro
N-Benzyl-4-piperidone
1-benzyl-1,2,3,6-tetrahydropyridin-4-yl trifluoromethanesulfonate

DownStream

1-phenyl-2-(1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl)ethanone
Rutaecarpine
Norharmane
3H-PYRIDO(3,4-B)INDOLE, 4,9-DIHYDRO
7-Nitro-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole
TERT-BUTYL 3,4-DIHYDRO-1H-PYRIDO[3,4-B]INDOLE-2(9H)-CARBOXYLATE
1,2,3,4-TETRAHYDRO-9-(PHENYLMETHYL)-PYRIDO[3,4-B]INDOLE
(1,2-DIMETHYL-1H-BENZOIMIDAZOL-5-YL)-(4-ETHOXY-BENZYL)-AMINE
2-methyltryptoline
9-Methyl-9H-Pyrido[3,4-b]indole hydrochloride

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Fingerprint analysis of thermolytic decarboxylation of tryptophan to tryptamine catalyzed by natural oils.

J. Chromatogr. A. 1210(1) , 115-20, (2008)

A number of N,N-dialkylated tryptamines show psychoactive properties in man which resulted in a renewed interest in psychopharmacological research. Attempts to manufacture these derivatives are increa...

Biosynthetic gene cluster for the cladoniamides, bis-indoles with a rearranged scaffold.

PLoS ONE 6(8) , e23694, (2011)

The cladoniamides are bis-indole alkaloids isolated from Streptomyces uncialis, a lichen-associated actinomycete strain. The cladoniamides have an unusual, indenotryptoline structure rarely observed a...

A class of oral N-[(1S,3S)-1-methyl-1,2,3,4-tetrahydro-β-carboline-3-carbonyl]- N'-(amino-acid-acyl)hydrazine: discovery, synthesis, in vitro anti-platelet aggregation/in vivo anti-thrombotic evaluation and 3D QSAR analysis.

Eur. J. Med. Chem. 46 , 3237-49, (2011)

The in vivo anti-thrombotic activities of amino acid modified tetrahydro-β-carbolines depended upon the proximity of the side chain of the amino acid residue to the carboline-cycle. Based on this prox...

5-(2-chloro-6-fluorobenzyl)-1-methyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
3-(3-fluorobenzamido)-N-(4-fluorophenyl)benzofuran-2-carboxamide
6-Chloro-2-oxobenz[cd]indole-1(2H)-propanenitrile
2-methoxy-4,5-dimethyl-N-(2-(1-methyl-1,2,3,4-tetrahydroquinolin-6-yl)-2-morpholinoethyl)benzenesulfonamide
3-Ethyl-7-[4-(4-nitrophenyl)piperazin-1-yl]triazolo[4,5-d]pyrimidine
(4-(3-(benzo[d][1,3]dioxol-5-yl)-1H-pyrazol-5-yl)-1,4-diazepan-1-yl)(thiophen-2-yl)methanone
2-Amino-4-(4-nitrophenyl)-5-oxo-1-[3-(trifluoromethyl)phenyl]-1,4,5,6,7,8-hexahydro-3-quinolinecarbonitrile
(1R,2S,4R)-N-(4-(N-propylsulfamoyl)phenyl)bicyclo[2.2.1]hept-5-ene-2-carboxamide
4-[(4-Methoxy-1-naphthyl)sulfonyl]morpholine
3-(3-methoxyphenyl)-1-(4-methylphenyl)-1-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-ylmethyl)urea

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