12-O-tetradecanoylphorbol-13-acetate

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Names

[ CAS No. ]:
16561-29-8

[ Name ]:
12-O-tetradecanoylphorbol-13-acetate

[Synonym ]:
4β-Phorbol 12-myristate 13-acetate
Tetradecanoic acid, (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-(acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa[3,4]benz[1,2-e]azulen-9-yl ester
TPA
PMA
12-O-Tetradecanoylphorbol-13-acetate
tetradecanoylphorbol acetate
MFCD00036736
phorbol 13-acetate 12-myristate
(1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-Acetoxy-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yl myristate
12-O-Tetradecanoylphorbol 13-acetate
4β,9α,12β,13α,20-Pentahydroxytiglia-1,6-dien-3-one 12-tetradecanoate 13-acetate
(1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-(acetyloxy)-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yl tetradecanoate
Phorbol 12-myristate 13-acetate

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
698.1±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C36H56O8

[ Molecular Weight ]:
616.825

[ Flash Point ]:
208.1±25.0 °C

[ Exact Mass ]:
616.397522

[ PSA ]:
130.36000

[ LogP ]:
7.71

[ Vapour Pressure ]:
0.0±5.0 mmHg at 25°C

[ Index of Refraction ]:
1.553

[ Water Solubility ]:
DMSO: DMSO solutions can be stored dark at −20?#x00b0;C for at least six months.soluble

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R38

[ Safety Phrases ]:
S36/37

[ RIDADR ]:
2928

[ WGK Germany ]:
3

[ RTECS ]:
QH4377000

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1(a)

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • phorbol
  • Phorbol-(12,13,20)-tri-n-tetradecanoat
  • Ethanoic anhydride
  • (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-3-(Acetoxymethyl)-4a,7b,9-trihydr oxy-1,1,6,8-tetramethyl-5-oxo-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro- 9aH-cyclopropa[3,4]benzo[1,2-e]azulen-9a-yl acetate
  • Myristoyl Chloride

DownStream

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Related Compounds

  • 12-O-Tetradecanoylphorbol-13-acetate-20-tetradecanoate
  • 12-O-Undecadienoylphorbol-13-acetate
  • 12-O-hexadecanoylphorbol-13-acetate
  • 12-O-(2Z,4E-octadienoyl)-phorbol-13-acetate
  • 12-O-2Z-4E-OCTADIENOYL-4-DEOXYPHORBOL-13-ACETATE
  • 12-O-tetradeca-2,4,6,8-tetranoylphorbol-13-acetate
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  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-{[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-methoxybutanamido]methyl}-1,3-thiazole-5-carboxylic acid
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine