(R)-2,3,5,6-tetrahydro-6-phenylimidazo[2,1-b]thiazole monohydrochloride

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Names

[ CAS No. ]:
16595-76-9

[ Name ]:
(R)-2,3,5,6-tetrahydro-6-phenylimidazo[2,1-b]thiazole monohydrochloride

[Synonym ]:
Dexamisole HCl
Dexamisole hydrochloride
levamisole hydrochloride
R 12,563
d-Tetramisole hydrochloride
EINECS 240-653-0

Chemical & Physical Properties

[ Boiling Point ]:
344.4ºC at 760 mmHg

[ Molecular Formula ]:
C11H13ClN2S

[ Molecular Weight ]:
240.75200

[ Flash Point ]:
162.1ºC

[ Exact Mass ]:
240.04900

[ PSA ]:
40.90000

[ LogP ]:
2.32160

[ Vapour Pressure ]:
6.61E-05mmHg at 25°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NJ5961000
CHEMICAL NAME :
Imidazo(2,1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (R)-(+)-
CAS REGISTRY NUMBER :
16595-76-9
LAST UPDATED :
199007
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C11-H12-N2-S.Cl-H
MOLECULAR WEIGHT :
240.77

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 11,169,1968

Safety Information

[ HS Code ]:
2934100090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Imidazo[2,1-b]thiazole,2,3,5,6-tetrahydro-6-phenyl-

DownStream

Customs

[ HS Code ]: 2934100090

[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Related Compounds

  • (2S)-2-{[1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylcyclohexyl]formamido}-3-methylbutanoic acid
  • 2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpentanamido]cyclohexane-1-carboxylic acid
  • 2-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-1,2,5-oxadiazole-3-amido]cyclohexane-1-carboxylic acid
  • 4-methyl-3-[(4-methyl-4H-1,2,4-triazol-3-yl)methyl]cyclohexan-1-amine
  • 4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-{[(1S)-1-phenylethyl]carbamoyl}butanoic acid
  • 2-(4-{2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-3-methylbutanoyl}piperazin-1-yl)acetic acid
  • 4-[(2-bromo-4-fluorophenyl)carbamoyl]-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid
  • 2-bromo-5-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanamido]-4-methylbenzoic acid
  • 3-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4,4,4-trifluorobutanamido]-3-methylbutanoic acid
  • 1-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4,4-difluorobutanamido]cyclopentane-1-carboxylic acid
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