3-Phenyl-1-indanone

Suppliers

Names

[ Name ]:
3-Phenyl-1-indanone

[Synonym ]:
1H-Inden-1-one, 2,3-dihydro-3-phenyl-
3-Phenyl-1-indanone
3-phenyl-2,3-dihydroinden-1-one
3-phenylindan-1-one
MFCD00037722

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
331.0±32.0 °C at 760 mmHg

[ Melting Point ]:
76-78ºC

[ Molecular Formula ]:
C₁₅H₁₂O

[ Molecular Weight ]:
208.255

[ Flash Point ]:
142.3±20.1 °C

[ Exact Mass ]:
208.088821

[ PSA ]:
17.07000

[ LogP ]:
3.46

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.621

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NK7538200

CHEMICAL NAME :: 1-Indanone, 3-phenyl-

CAS REGISTRY NUMBER :: 16618-72-7

BEILSTEIN REFERENCE NO. :: 1370263

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C15-H12-O

MOLECULAR WEIGHT :: 208.27

WISWESSER LINE NOTATION :: L56 BVT&J DR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 22,1464,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#02960

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S22-S36/37

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
NK7538200

[ HS Code ]:
2914399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

3,3-Diphenylpropanoic acid
2-(1-phenyl-vinyl)benzaldehyde
Cinnamic acid
benzene
Cinnamic acid
(E)-1-(2-bromophenyl)-3-phenylprop-2-en-1-one
Benzenemethanol, a-(2-phenylethynyl)-
3,3-diphenylpropanoyl chloride
(E)-Chalcone

DownStream

1-Phenyl-1H-indene
2-bromo-3-phenylinden-1-one
2-Hydroxyaethyl-diphenylthioarsinit
2-bromo-3-phenyl-1-indanone
2,3-dibromo-3-phenyl-2H-inden-1-one
1-Phenyl-5-acenaphtheneacetic acid
1-Indanpropionic acid, 3-phenyl-
2,2-dimethyl-5-propan-2-yl-1,3-dioxane-4,6-dione
2,2-dimethyl-5-(3'-phenyl-2',3'-dihydro-1'H-inden-1'-ylidene)-1,3-dioxan-4,6-dione

Customs

[ HS Code ]: 2914399090

[ Summary ]:
2914399090. other aromatic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles

Asymmetric total synthesis of (+)-indatraline via diastereoselective amination of chiral ethers using chlorosulfonyl isocyanate. Lee SH, et al.

Tetrahedron 69(7) , 1877-80, (2013)

Thermolysis of substituted indenes. Sigmatropic phenyl and hydrogen migrations. Miller LL and Boyer RF.

J. Am. Chem. Soc. 93(3) , 650-56, (1971)

Koltunov KY.

Tetrahedron Lett. 48(32) , 5631-34, (2007)