5-METHOXYGRAMINE

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Names

[ CAS No. ]:
16620-52-3

[ Name ]:
5-METHOXYGRAMINE

[Synonym ]:
1-(5-methoxy-1H-indol-3-yl)-N,N-dimethylmethanamine
EINECS 240-669-8
5-METHOXYGRAMINE
MFCD00005630

Chemical & Physical Properties

[ Density]:
1.119g/cm3

[ Boiling Point ]:
334.7ºC at 760 mmHg

[ Melting Point ]:
123-126 °C(lit.)

[ Molecular Formula ]:
C12H16N2O

[ Molecular Weight ]:
204.26800

[ Flash Point ]:
156.2ºC

[ Exact Mass ]:
204.12600

[ PSA ]:
28.26000

[ LogP ]:
2.23810

[ Vapour Pressure ]:
0.000126mmHg at 25°C

[ Storage condition ]:
Refrigerator (+4°C)

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NL7700000
CHEMICAL NAME :
Indole, 3-((dimethylamino)methyl)-5-methoxy-
CAS REGISTRY NUMBER :
16620-52-3
BEILSTEIN REFERENCE NO. :
0170533
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C12-H16-N2-O
MOLECULAR WEIGHT :
204.30
WISWESSER LINE NOTATION :
T56 BMJ D1N1&1 GO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
130 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PSYPAG Psychopharmacologia (Berlin). (Berlin, Ger.) V.1-46, 1959-76. For publisher information, see PSCHDL. Volume(issue)/page/year: 16,385,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
56 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#04863

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
C: Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
NL7700000

[ HS Code ]:
2933990090

Synthetic Route

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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The effect of ligand pretreatment on human 5-hydroxytryptamine2C (5-HT2C) receptors was examined in CHO cells expressing high (CHO-1C7; 67+/-3 pmol/mg) or low (CHO-1C19; 72+/-10 fmol/mg) levels of the...

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Related Compounds

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  • 5-(3-formyl-2-hydroxyphenyl)benzene-1,3-dicarboxylic acid
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  • 5-(p-Toluenesulfonate)-2,3-O-isopropylidene-2-C-methyl-D-ribonic-gamma-lactone
  • 5-(oxiran-2-ylmethoxy)-2,3,4,9-tetrahydro-1H-carbazole
  • 5-(2,4-difluorophenyl)-2-hydroxy-3-sulfooxybenzoic acid
  • N-ethyl-3-(3-fluorobenzyl)tetrahydro-2H-pyran-4-sulfonamide
  • N-ethyl-3-(2-methylbenzyl)tetrahydro-2H-pyran-4-sulfonamide
  • 3-(2-cyanobenzyl)-N-ethyltetrahydro-2H-pyran-4-sulfonamide
  • 3-(2-chlorobenzyl)-N-ethyltetrahydro-2H-pyran-4-sulfonamide
  • 1-(2,5-dichlorophenyl)-N-ethylmethanesulfonamide
  • N-ethyl-1-(1-methyl-1H-imidazol-2-yl)methanesulfonamide
  • 5-cyclopropyl-N-((5-(furan-2-carbonyl)thiophen-2-yl)methyl)isoxazole-3-carboxamide
  • 1-(1-cyclopropyl-1H-imidazol-2-yl)-N-ethylmethanesulfonamide
  • (S)-tert-butyl 3-(2-ethoxy-2-oxoethyl)pyrrolidine-1-carboxylate
  • (S)-benzyl 3-(2-ethoxy-2-oxoethyl)pyrrolidine-1-carboxylate
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