2-thienylsulfonyl chloride

Suppliers

Names

[ CAS No. ]:
16629-19-9

[ Name ]:
2-thienylsulfonyl chloride

[Synonym ]:
2-Thiophenesulfonyl chloride
2-Thiophenesulfonylchloride
thiophene-2-sulphonylchloride
MFCD00005426
Thiophen-2-sulfonylchlorid
Thiophene-2-sulfonyl chloride
EINECS 240-677-1
2-thienylsulfonyl chloride

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
265.2±13.0 °C at 760 mmHg

[ Melting Point ]:
30-32 °C(lit.)

[ Molecular Formula ]:
C4H3ClO2S2

[ Molecular Weight ]:
182.648

[ Flash Point ]:
114.2±19.8 °C

[ Exact Mass ]:
181.926300

[ PSA ]:
70.76000

[ LogP ]:
1.59

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.581

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45-S28A-S25

[ RIDADR ]:
UN 3261 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
29349990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Thiophene(SIV)
  • 2-Thiophenesulfonic acid
  • 2-Iodothiophene
  • 2-(Tributylstannyl)Thiophene

DownStream

  • 2,2'-Bithiophene
  • (3R)-3-Benzyl-4-(2-thienylsulfonyl)-2,3,4,5-tetrahydro-1H-1,4-ben zodiazepine-7-carbonitrile
  • SR3335
  • 2-Thienylthiol
  • 2-Thienyl disulfide
  • 5-Chloro-2-thiophenesulfonamide
  • 2-Thiophenesulfonamide
  • N-tert-Butyl-2-thiophenesulfonamide
  • 1-(THIOPHENE-2-SULFONYL)-PIPERIDINE-4-CARBOXYLIC ACID
  • n-[2-thiophene]sulfonyl[4-iodo]aniline

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Discovery of inhibitors of the mitotic kinase TTK based on N-(3-(3-sulfamoylphenyl)-1H-indazol-5-yl)-acetamides and carboxamides.

Bioorg. Med. Chem. 22(17) , 4968-97, (2014)

TTK kinase was identified by in-house siRNA screen and pursued as a tractable, novel target for cancer treatment. A screening campaign and systematic optimization, supported by computer modeling led t...

Concerted solvent processes for common sulfonyl chloride precursors used in the synthesis of sulfonamide-based drugs.

Int. J. Mol. Sci. 9(5) , 914-25, (2008)

Specific rates of solvolysis in hydroxylic solvents available for the solvolysis of 2-thiophenesulfonyl chloride and phenylmethanesulfonyl chloride are supplemented by determining the values in fluoro...

Reaction kinetics of 3-thiophenesulfonyl chloride with anilines in methanol. Arcoria A, et al.

J. Org. Chem. 39(12) , 1689-1691, (1974)


More Articles

Related Compounds

  • 5-chloro-2-thienylsulfonyl chloride
  • 3-Methyl-2-thienylsulfonyl chloride
  • 5-chloro-4-nitro-2-thienylsulfonyl chloride
  • Benzenecarboximidoyl chloride, N-(2-thienylsulfonyl)
  • 1-(2-THIENYLSULFONYL)-1H-BENZOTRIAZOLE
  • lead,oxygen(2-),chloride
  • 3-(Diphenylmethyl)benzenamine
  • 3-Hydroxyphthalamide
  • 2-(Vinyloxy)acetic acid
  • 1-Quinolin-6-yl-butan-1-one
  • 2-Thioxosuccinic acid
  • 2-Nitro-5-(2,2,2-trifluoroethoxy)benzoic acid
  • {3-[(Cyclohexyloxy)methyl]phenyl}methanamine
  • 2-[(5-Chloropyridin-2-yl)(methyl)amino]acetic acid
  • 2,5-dimethyl-1-(pyridin-4-yl)-1H-pyrrole-3-carboxylic acid
  • 3,6-DI-O-Tert-butyldiphenylsilyl-D-galactal
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