NLRP3-IN-2

Suppliers

Names

[ Name ]:
NLRP3-IN-2

[Synonym ]:
5-chloro-2-methoxy-N-[2-(4-sulphamoylphenyl)ethyl]benzamide
Benzamide, N-[2-[4-(aminosulfonyl)phenyl]ethyl]-5-chloro-2-methoxy-
5-Chloro-2-methoxy-N-[2-(4-sulfamoylphenyl)ethyl]benzamide
4-[2-(5-chloro-2-methoxy-benzamide)ethyl]-benzenesulphonamide
EINECS 240-722-5
5-Chloro-2-methoxy-N-(4-sulfamoylphenethyl)benzamide
MFCD00193756

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Melting Point ]:
209-214 °C

[ Molecular Formula ]:
C₁₆H₁₇ClN₂O₄S

[ Molecular Weight ]:
368.835

[ Exact Mass ]:
368.059753

[ PSA ]:
106.87000

[ LogP ]:
1.74

[ Index of Refraction ]:
1.598

[ Storage condition ]:
Refrigerator

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
T

[ Risk Phrases ]:
R23/24/25

[ Safety Phrases ]:
S26-S36-S36/37-S22

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2935009090

Precursor & DownStream

Precursor

5-chloro-2-methoxybenzoyl chloride
4-(2-aminoethyl)benzene sulfonmide

DownStream

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Articles

A novel pharmacologic inhibitor of the NLRP3 inflammasome limits myocardial injury after ischemia-reperfusion in the mouse.

J. Cardiovasc. Pharmacol. 63(4) , 316-22, (2014)

The formation of the NLRP3 inflammasome in the heart during acute myocardial infarction amplifies the inflammatory response and mediates further damage. Glyburide has NLRP3 inhibitory activity in vitr...

Trendelenburg G.

J. Cereb. Blood Flow Metab. , (2014)

Reply to Letter Regarding Article," NLRP3 Inflammasome as a Therapeutic Target in Myocardial Infarction. Takahashi M.

Int. Heart J. 55(4) , 380, (2014)

NLRP3/AIM2-IN-2
NLRP3-IN-5
NLRP3-IN-3
NLRP3-IN-10
NLRP3-IN-11
NLRP3-IN-14
Ethyl 3-[1-(aminothioxomethyl)-5-hydroxy-1H-pyrazol-4-yl]benzoate
N-[(2S)-2-(diethylamino)propyl]benzamide
7-Methoxy-4-nitro-1-(phenylsulfonyl)indole
5-Bromo-2-hydrazinylpyrimidine hydrochloride
4-Nitrophenyl (pyren-1-ylmethyl) carbonate
2-[(Pyridin-2-yl)amino]acetonitrile hydrochloride
2-[2-(2-Methylprop-1-yloxy)phenoxy]ethyl methanesulfonate
2-[3,5-Bis(trifluoromethyl)phenyl]ethylhydrazine
2-[1-(difluoromethyl)-1H-pyrazol-4-yl]ethan-1-amine
2-Amino-3-(3-fluoro-2-hydroxyphenyl)propanoic acid

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