2-(3-Chloropropyl)-1,3-dioxolane

Names

[ CAS No. ]:
16686-11-6

[ Name ]:
2-(3-Chloropropyl)-1,3-dioxolane

[Synonym ]:
MFCD00043135
1,3-Dioxolane, 2-(3-chloropropyl)-
2-(3-Chloropropyl)-1,3-dioxolane

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
199.5±15.0 °C at 760 mmHg

[ Molecular Formula ]:
C₆H₁₁ClO₂

[ Molecular Weight ]:
150.603

[ Flash Point ]:
75.3±15.6 °C

[ Exact Mass ]:
150.044754

[ PSA ]:
18.46000

[ LogP ]:
0.67

[ Vapour Pressure ]:
0.5±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.439

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S23;S24/25

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2932999099

Precursor & DownStream

Precursor

4-Chloro-Butyraldehyde
Ethylene glycol

DownStream

5-Fluorotryptamine
see 1,3-Dioxolane,2-propyl-
2-(5-(TRIFLUOROMETHYL)-1H-INDOL-3-YL)ETHANAMINE HYDROCHLORIDE
2-cyclobutyloxyethanol
2,3,4,5-Tetrahydropyridazine
3-(1,3-dioxolan-2-yl)propanenitrile
2-(3-iodopropyl)-1,3-dioxolane

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

High yield conversion of doxorubicin to 2-pyrrolinodoxorubicin, an analog 500-1000 times more potent: structure-activity relationship of daunosamine-modified derivatives of doxorubicin.

Proc. Natl. Acad. Sci. U. S. A. 93(6) , 2464-2469, (1996)

A convenient, high yield conversion of doxorubicin to 3'-deamino-3'-(2''-pyrroline-1''-yl)doxorubicin is described. This daunosamine-modified analog of doxorubicin is 500-1000 times more active in vit...

P.A. Aristoff

J. Org. Chem. 50 , 1765, (1985)

S.A. Bal et al.

J. Org. Chem. 47 , 5045, (1982)

2-phenyl-2-(3-chloropropyl)-1,3-dioxolane
2-methyl-2-(3-chloropropyl)-1,3-dioxolane
2-propyl-2-(3-chloropropyl)-1,3-dioxolane
2-(4-bromophenyl)-2-(3-chloropropyl)-1,3-dioxolane
2-(3-chloropropyl)-2-cyclohexyl-1,3-dioxolane
2-(3-chloropropyl)-2-ethoxy-1,3-dioxolane
N-[(5-phenyl-1,3-thiazol-2-yl)methyl]prop-2-enamide
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
tert-Butyl-DL-alanine
4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide