Acetylcyclopentanone

Names

[ Name ]:
Acetylcyclopentanone

[Synonym ]:
Cyclopentanone, 2-acetyl-
2-acetylcyclopentan-1-one
MFCD00001413
2-Acetylcyclopentanone
Acetylcyclopentanone
EINECS 216-797-5

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
197.2±0.0 °C at 760 mmHg

[ Melting Point ]:
60-70℃

[ Molecular Formula ]:
C₇H₁₀O₂

[ Molecular Weight ]:
126.153

[ Flash Point ]:
72.8±0.0 °C

[ Exact Mass ]:
126.068077

[ PSA ]:
34.14000

[ LogP ]:
-0.48

[ Vapour Pressure ]:
0.4±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.468

[ Storage condition ]:
2-8°C

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GY4728000

CHEMICAL NAME :: Cyclopentanone, 2-acetyl-

CAS REGISTRY NUMBER :: 1670-46-8

BEILSTEIN REFERENCE NO. :: 1857601

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C7-H10-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 840 uL/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - changes in structure or function of salivary glands

REFERENCE :: ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 1,680,1992

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S36

[ WGK Germany ]:
3

[ RTECS ]:
GY4728000

[ HS Code ]:
2914299000

Precursor & DownStream

Precursor

Ethanoic anhydride
Cyclopentanone
1-trimethylsiloxycyclopentene
Acetyl chloride
acetyl fluoride
6-methyl-7-oxabicyclo[4.1.0]heptan-5-one
2-METHYL-2-CYCLOHEXEN-1-ONE
6-Oxoheptanoic acid
2-(1-methoxyethylidene)cyclopentan-1-one

DownStream

2-acetyl-2-(3-oxobutyl)cyclopentan-1-one
Glutaric acid
Glutaric Anhydride
5,6-dioxo-n-heptanoic acid
(2-oxocyclopentyl) acetate
1-acetyl-6-oxabicyclo[3.1.0]hexan-2-one
trioxane
gamma-Butyrolactone

Customs

[ HS Code ]: 2914299000

[ Summary ]:
2914299000. other cyclanic, cyclenic or cyclotherpenic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles

Protective properties of 2-acetylcyclopentanone in a mouse model of acetaminophen hepatotoxicity.

J. Pharmacol. Exp. Ther. 346(2) , 259-69, (2013)

Our previous research showed that enolates formed from 1,3-dicarbonyl compounds, such as 2-acetylcyclopentanone (2-ACP), could provide protection in cell culture models from electrophile- or oxidative...

Ultrafast vibrational population transfer dynamics in 2-acetylcyclopentanone studied by 2D IR spectroscopy.

ChemPhysChem 12(4) , 799-805, (2011)

2-Acetylcyclopentanone (2-ACP), which is a β-dicarbonyl compound, undergoes keto-enol isomerization, and its enol tautomers are stabilized by a cyclic intramolecular hydrogen bond. 2-ACP (keto form) h...