2,6-Dimethoxypyridine-3-carboxylic acid

Names

[ CAS No. ]:
16727-43-8

[ Name ]:
2,6-Dimethoxypyridine-3-carboxylic acid

[Synonym ]:
MFCD00075582
2,6-Dimethoxynicotinic acid

Chemical & Physical Properties

[ Density]:
1.279 g/cm3

[ Boiling Point ]:
293.1ºC at 760 mmHg

[ Melting Point ]:
140-144ºC(lit.)

[ Molecular Formula ]:
C₈H₉NO₄

[ Molecular Weight ]:
183.16100

[ Flash Point ]:
131ºC

[ Exact Mass ]:
183.05300

[ PSA ]:
68.65000

[ LogP ]:
0.79700

[ Appearance of Characters ]:
Crystalline Powder | White to pale yellow

[ Vapour Pressure ]:
0.000805mmHg at 25°C

[ Index of Refraction ]:
1.535

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Methanol
2,6-Dichloronicotinic acid

DownStream

2,6-dimethoxypyridine-3-carbonitrile
3-ACETYL-2,6-DIMETHOXYPYRIDINE
3-Pyridinecarbonyl chloride, 2,6-dimethoxy- (9CI)
ethyl 2,6-dimethoxypyridine-3-carboxylate

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Study of the anticancer properties of tin(IV) carboxylate complexes on a panel of human tumor cell lines.

ChemMedChem 7(2) , 301-10, (2012)

A group of organotin(IV) complexes were prepared: [SnCy3 (DMNI)] (1), [SnCy3 (BZDO)] (2), [SnCy3 (DMFU)] (3), and [SnPh2 (BZDO)2 ] (4), for which DMNIH=2,6-dimethoxynicotinic acid, BZDOH=1,4-benzodiox...

Antitubercular activities of novel benzothiazolo naphthyridone carboxylic acid derivatives endowed with high activity toward multi-drug resistant tuberculosis.

Biomed. Pharmacother. 63 , 11-18, (2009)

Sixteen novel 3-nitro-2-(sub)-5,12-dihydro-5-oxobenzothiazolo[3,2-a]-1,8-naphthyridine-6-carboxylic acids were synthesized from 2,6-dimethoxynicotinic acid and 2-aminothiophenol and evaluated for thei...

One ligand different metal complexes: Biological studies of titanium (IV), tin (IV) and gallium (III) derivatives with the 2, 6-dimethoxypyridine-3-carboxylato ligand. Gómez-Ruiz S, et al.

J. Organomet. Chem. 696(20) , 3206-13, (2011)

5-Bromo-2,6-dimethoxypyridine-3-carboxylic acid
2,6-Dimethoxypyridine-3-carboxylic acid methyl ester
2-(2,4-dimethylphenyl)benzoic acid
5,6-Dimethoxynicotinic acid
2,6-Dimethoxypyridine-3-boronic acid pinacol ester
2,6-DIMETHYLQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
4-Tert-butyl-N-(7-(tert-butyldimethylsilyloxy)naphthalen-1-YL)thiazol-2-amine
{1-[(2,4-Difluorophenyl)methyl]piperidin-3-yl}methanol
5,7-Bis(trifluoromethyl)quinoline-4-thiol
Methyl 2,3,3,3-tetrafluoro-2-[(undecafluoropentyl)oxy]propanoate
3-(Trifluoromethyl)naphtho[1,2-c]isoxazole-5-carboxylic acid
Hexafluoropropylene oxide trimer
2,2-Difluoro-2-(pyridin-2-yl)acetohydrazide
4-[Difluoro(pyridin-2-yl)acetyl]piperazine, N1-BOC protected
2-Amino-6-(pentafluoroethylthio)benzonitrile
2-Bromo-6-(pentafluoroethylthio)benzonitrile

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