1-Methylbiguanide monohydrochloride
Suppliers
Names
[ CAS No. ]:
1674-62-0
[ Name ]:
1-Methylbiguanide monohydrochloride
[Synonym ]:
1-(diaminomethylidene)-2-methylguanidine,hydrochloride
Metformin Related Compound B
1-Methylbiguanide hyrdochloride (Metformin RCB)
Metformin Impurity 5(HCl)
Chemical & Physical Properties
[ Density]:
1.45g/cm3
[ Boiling Point ]:
295.3ºC at 760mmHg
[ Molecular Formula ]:
C3H10ClN5
[ Molecular Weight ]:
151.59800
[ Flash Point ]:
132.4ºC
[ Exact Mass ]:
151.06200
[ PSA ]:
97.78000
[ LogP ]:
1.10720
[ Vapour Pressure ]:
0.00154mmHg at 25°C
[ Index of Refraction ]:
1.624
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DU2042000
- CHEMICAL NAME :
- Biguanide, 1-methyl-, monohydrochloride
- CAS REGISTRY NUMBER :
- 1674-62-0
- LAST UPDATED :
- 198702
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C3-H9-N5.Cl-H
- MOLECULAR WEIGHT :
- 151.63
- WISWESSER LINE NOTATION :
- MUYZMYUM&M1 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1754 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 15,521,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 325 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 15,521,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1750 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 12,314,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 470 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PLRCAT Pharmacological Research Communications. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1969- Volume(issue)/page/year: 6,117,1974
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302
[ Precautionary Statements ]:
P301 + P312 + P330
[ RIDADR ]:
NONH for all modes of transport