fluphenazine sulfoxide

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Names

[ CAS No. ]:
1674-76-6

[ Name ]:
fluphenazine sulfoxide

[Synonym ]:
Fluphenazine sulphoxide
Fluphenazine sulfoxide
2-[4-[3-[5-oxo-2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol

Chemical & Physical Properties

[ Density]:
1.43g/cm3

[ Boiling Point ]:
615.4ºC at 760mmHg

[ Melting Point ]:
131-133ºC

[ Molecular Formula ]:
C22H26F3N3O2S

[ Molecular Weight ]:
453.52100

[ Flash Point ]:
326ºC

[ Exact Mass ]:
453.17000

[ PSA ]:
66.23000

[ LogP ]:
4.13010

[ Vapour Pressure ]:
5.28E-16mmHg at 25°C

[ Index of Refraction ]:
1.654

[ Storage condition ]:
2-8°C

Articles

Plasma levels of fluphenazine in patients receiving fluphenazine decanoate. Relationship to clinical response.

Br. J. Psychiatry 158 , 658-65, (1991)

The levels of fluphenazine and fluphenazine sulphoxide in schizophrenic patients who were randomly assigned to receive either 5 mg or 25 mg of fluphenazine decanoate every two weeks were monitored. Pa...

Impact of clinical pharmacokinetics on neuroleptic therapy in patients with schizophrenia.

J. Psychiatry Neurosci. 19(4) , 254-64, (1994)

This review covers some recent work on: 1. The effects of route of administration on the pharmacokinetics of fluphenazine and some of its metabolites; 2. The clinical pharmacokinetics of fluphenazine ...

The sulfoxidation of fluphenazine in schizophrenic patients maintained on fluphenazine decanoate.

Psychopharmacology 93(3) , 369-73, (1987)

Highly sensitive radioimmunoassays were applied to study the sulfoxidation of fluphenazine in 30 schizophrenic patients maintained on either 5 mg or 25 mg fluphenazine decanoate by intramuscular injec...


More Articles

Related Compounds

  • Fluphenazine (dihydrochloride)
  • Fluphenazine
  • FLUPHENAZINE ENANTHATE DIHYDROCHLORIDE (125 MG)
  • Fluphenazine decanoate
  • Fluphenazine enanthate
  • fluphenazine n-mustard dihydrochloride
  • 4-(2,5-dioxopyrrolidin-1-yl)-N-(pyridin-3-yl(tetrahydro-2H-pyran-4-yl)methyl)benzenesulfonamide
  • 3,3,3-trifluoro-N-(pyridin-3-yl(tetrahydro-2H-pyran-4-yl)methyl)propane-1-sulfonamide
  • furan-2-yl(3-(4-(phenoxymethyl)-1H-1,2,3-triazol-1-yl)azetidin-1-yl)methanone
  • (3-(4-(phenoxymethyl)-1H-1,2,3-triazol-1-yl)azetidin-1-yl)(pyrazin-2-yl)methanone
  • 1-(3-(4-(phenoxymethyl)-1H-1,2,3-triazol-1-yl)azetidin-1-yl)-2-(thiophen-2-yl)ethanone
  • (E)-1-(3-(4-(phenoxymethyl)-1H-1,2,3-triazol-1-yl)azetidin-1-yl)-3-(thiophen-2-yl)prop-2-en-1-one
  • benzo[d][1,3]dioxol-5-yl(3-(4-(phenoxymethyl)-1H-1,2,3-triazol-1-yl)azetidin-1-yl)methanone
  • (2-(methylthio)pyridin-3-yl)(3-(4-(phenoxymethyl)-1H-1,2,3-triazol-1-yl)azetidin-1-yl)methanone
  • 2-(2-chlorophenyl)-1-(3-(4-(phenoxymethyl)-1H-1,2,3-triazol-1-yl)azetidin-1-yl)ethanone
  • (2-chloro-4-fluorophenyl)(3-(4-(phenoxymethyl)-1H-1,2,3-triazol-1-yl)azetidin-1-yl)methanone
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