fluphenazine sulfoxide
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Names
[ CAS No. ]:
1674-76-6
[ Name ]:
fluphenazine sulfoxide
[Synonym ]:
Fluphenazine sulphoxide
Fluphenazine sulfoxide
2-[4-[3-[5-oxo-2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol
Chemical & Physical Properties
[ Density]:
1.43g/cm3
[ Boiling Point ]:
615.4ºC at 760mmHg
[ Melting Point ]:
131-133ºC
[ Molecular Formula ]:
C22H26F3N3O2S
[ Molecular Weight ]:
453.52100
[ Flash Point ]:
326ºC
[ Exact Mass ]:
453.17000
[ PSA ]:
66.23000
[ LogP ]:
4.13010
[ Vapour Pressure ]:
5.28E-16mmHg at 25°C
[ Index of Refraction ]:
1.654
[ Storage condition ]:
2-8°C
Articles
Br. J. Psychiatry 158 , 658-65, (1991)
The levels of fluphenazine and fluphenazine sulphoxide in schizophrenic patients who were randomly assigned to receive either 5 mg or 25 mg of fluphenazine decanoate every two weeks were monitored. Pa...
J. Psychiatry Neurosci. 19(4) , 254-64, (1994)
This review covers some recent work on: 1. The effects of route of administration on the pharmacokinetics of fluphenazine and some of its metabolites; 2. The clinical pharmacokinetics of fluphenazine ...
Psychopharmacology 93(3) , 369-73, (1987)
Highly sensitive radioimmunoassays were applied to study the sulfoxidation of fluphenazine in 30 schizophrenic patients maintained on either 5 mg or 25 mg fluphenazine decanoate by intramuscular injec...