tert-Butyl 5-fluorospiro[indoline-3,4'-piperidine]-1'-carboxylate

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Names

[ CAS No. ]:
167484-91-5

[ Name ]:
tert-Butyl 5-fluorospiro[indoline-3,4'-piperidine]-1'-carboxylate

[Synonym ]:
tert-butyl 5-fluorospiro[1,2-dihydroindole-3,4'-piperidine]-1'-carboxylate

Chemical & Physical Properties

[ Density]:
1.201g/cm3

[ Boiling Point ]:
424.621ºC at 760 mmHg

[ Molecular Formula ]:
C17H23FN2O2

[ Molecular Weight ]:
306.37500

[ Flash Point ]:
210.604ºC

[ Exact Mass ]:
306.17400

[ PSA ]:
41.57000

[ LogP ]:
3.59580

[ Index of Refraction ]:
1.565

[ Storage condition ]:
2-8°C

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • tert-butyl-5-fluorospiro[indole-3,4'-piperidine]-1'-carboxylate
  • 4-methoxymethylenepiperidine-1-carboxylic acid tert-butyl ester
  • N-(tert-Butoxycarbonyl)-4-piperidone

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 2-{[1-(5-Cyclopropyl-1,3,4-thiadiazol-2-yl)piperidin-4-yl]oxy}-5-methoxypyrimidine
  • 4-(2-{4-[(3,5-Dimethyl-1,2-oxazol-4-yl)methyl]piperazin-1-yl}-6-methylpyrimidin-4-yl)morpholine
  • 4,6-Dimethoxy-2-[4-(1,2,5-thiadiazol-3-yl)piperazin-1-yl]pyrimidine
  • N-[1-(3-cyano-4,6-dimethylpyridin-2-yl)piperidin-4-yl]cyclopropanesulfonamide
  • 3-[4-(2,3-Dimethylphenyl)piperazin-1-yl]-1-methyl-1,2-dihydropyrazin-2-one
  • 2-(Methylsulfanyl)-4-{4-[(pyrazin-2-yloxy)methyl]piperidin-1-yl}pyrimidine
  • 2-{3-[(1H-imidazol-1-yl)methyl]azetidin-1-yl}-4,6-dimethoxy-1,3,5-triazine
  • N,6-dimethyl-2-(methylsulfanyl)-N-[1-(pyridin-2-yl)azetidin-3-yl]pyrimidin-4-amine
  • 1-Cyclopropanecarbonyl-4-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]piperazine
  • 4-Ethyl-5-fluoro-6-(3-{[(5-fluoropyridin-2-yl)oxy]methyl}pyrrolidin-1-yl)pyrimidine
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