2-(Methylamino)propanenitrile

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Names

[ CAS No. ]:
16752-54-8

[ Name ]:
2-(Methylamino)propanenitrile

[Synonym ]:
N-Methyl-DL-alanin-nitril
N-cyanoethyl-N-methylamine
DL-2-Methylamino-propionsaeure-nitril
methylaminopropionitrile
DL-2-Methylamino-propionitril
N-methyl-DL-alanine nitrile

Chemical & Physical Properties

[ Density]:
0.865g/cm3

[ Boiling Point ]:
157.2ºC at 760mmHg

[ Molecular Formula ]:
C4H8N2

[ Molecular Weight ]:
84.11970

[ Flash Point ]:
48.9ºC

[ Exact Mass ]:
84.06870

[ PSA ]:
35.82000

[ LogP ]:
0.50878

[ Vapour Pressure ]:
2.79mmHg at 25°C

[ Index of Refraction ]:
1.409

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TZ4905000
CHEMICAL NAME :
Propanenitrile, 2-(methylamino)-
CAS REGISTRY NUMBER :
16752-54-8
LAST UPDATED :
199806
DATA ITEMS CITED :
4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
48 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - tremor Lungs, Thorax, or Respiration - other changes
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0545552
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1990 mg/m3/1H
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - other changes Blood - hemorrhage
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0545810
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
50100 ug/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Liver - other changes Blood - other changes
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0545552

Safety Information

[ HS Code ]:
2926909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Sodium cyanide
  • Methylamine hydrochloride
  • ch3cho
  • POTASSIUM CYANIDE
  • methylamine
  • HYDROGEN CYANIDE
  • Lactonitrile
  • cyanide
  • Dimethylamine
  • Water

DownStream

  • 2-[1-cyanoethyl(methyl)amino]propanenitrile
  • Lactonitrile
  • N-Me-DL-Ala-OH.HCl
  • N~2~-methylalaninamide(SALTDATA: FREE)

Customs

[ HS Code ]: 2926909090

[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Related Compounds

  • 2-Methyl-2-(methylamino)propanenitrile
  • 2-(methylamino)propanenitrile,hydrochloride
  • 2-(3-methoxyphenyl)-2-(methylamino)propanenitrile
  • 2-methylamino-3-phenyl-propanenitrile
  • 2-methyl-3-methylamino-propanenitrile
  • 2-(Methylamino)methyl-1,6,7,11b-tetrahydro-2H-dibenz(cd,h)azuzene hydrochloride
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 1-(4-{3-[(2-ethyl-1H-imidazol-1-yl)methyl]azetidine-1-carbonyl}phenyl)pyrrolidine-2,5-dione
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 6-(Aminomethyl)-5-fluoropyridin-2-amine