4-Hydroxy-1-Methyl-2-quinolone

Suppliers

Names

[ Name ]:
4-Hydroxy-1-Methyl-2-quinolone

[Synonym ]:
4-hydroxy-1-methyl-1,2-dihydro-2-quinolinone
1-methyl-4-hydroxy-2(1H)-quinolinone
4-Hydroxy-1-methyl-2-quinolone
4-Hydroxy-1-methyl-2(1H)-quinolinone
4-Hydroxy-N-methylcarbostyril
N-methyl-4-hydroxyquinolin-2(1H)-one
EINECS 216-830-3
1-methyl-4-hydroxyquinolin-2(1H)-one
4-Hydroxy-1-methyl-2(1H)-quinolone
4-hydroxy-1-methylquinolin-2(1H)-one
4-hydroxy-1-methyl-2-quinolinone
4-Hydroxy-1-methylcarbostyril
2(1H)-Quinolinone,4-hydroxy-1-methyl
1-Methyl-4-hydroxycarbostyril
CARBOSTYRIL,4-HYDROXY-1-METHYL
4-Hydroxy-1-methyl-1H-quinolin-2-one
MFCD00024052
1,2-dihydro-4-hydroxy-N-methylquinolin-2-one
2(1H)-Quinolinone, 4-hydroxy-1-methyl-

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
297.6±40.0 °C at 760 mmHg

[ Melting Point ]:
269-271 °C(lit.)

[ Molecular Formula ]:
C₁₀H₉NO₂

[ Molecular Weight ]:
175.184

[ Flash Point ]:
133.8±27.3 °C

[ Exact Mass ]:
175.063324

[ PSA ]:
42.23000

[ LogP ]:
1.31

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.647

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
FG7350000

[ HS Code ]:
2933790090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

methyl 2-(N-bromoacetyl-N-methylamino)benzoate
3-ACETYL-4-HYDROXY-1-METHYL-2(1H)-QUINOLINONE
N-Methylanthranilic acid
Ethanoic anhydride
1,2-DIHYDRO-4-HYDROXY-1-METHYL-2-OXO-3-QUINOLINECARBOXYLIC ACID ETHYL ESTER
N-Methylaniline
malonoyl chloride
4-Hydroxy-6-Methyl-2H-Pyrano[3,2-c]Quinoline-2,5(6H)-Dione
1-methyl-2,4-dioxo-quinoline-3-carboxylic acid

DownStream

(1-methyl-2-oxoquinolin-4-yl) 4-methylbenzenesulfonate
4-amino-1-methyl-3-nitroquinolin-2-one
5-methyl-3-oxido-[1,2,5]oxadiazolo[3,4-c]quinolin-3-ium-4-one
3,3-dichloro-1-methylquinoline-2,4-dione
4-Chloro-1-methyl-3-nitroquinolin-2(1H)-one
1-methylisatin
Furo[3,2-c]quinolin-4(2H)-one, 3,5-dihydro-5-methyl-2-(1-methylethenyl)
N-Methyl-4-(propan-2-onyl)oxy-chinolin-2(1H)-on
Zanthobisquinolone
2(1H)-Quinolinone,4-chloro-1-methyl-

Customs

[ HS Code ]: 2933790090

[ Summary ]:
2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

Articles

Over-expression of bael quinolone synthase in tobacco improves plant vigor under favorable conditions, drought, or salt stress.

FEBS Lett. 589(3) , 332-41, (2015)

Type III polyketide synthases (PKSs) catalyze the biosynthesis of various medicinally important secondary metabolites in plants, but their role in growth and stress response is unclear. Here, we overe...

Mechanistic study of electrochemical oxidation of catechols in the presence of 4-hydroxy-1-methyl-2 (1H)-quinolone: Application to the electrochemical synthesis. Fakhari AR, et al.

Electrochim. Acta 50(27) , 5322-5328, (2005)

Ceric ammonium nitrate (CAN)-mediated oxidative cycloaddition of 1, 3-dicarbonyls to conjugated compounds. Efficient synthesis of dihydrofurans, dihydrofurocoumarins, dihydrofuroquinolinones, dihydrofurophenalenones, and furonaphthoquinone natural products. Lee YR, et al.

Tetrahedron 56(45) , 8845-53, (2000)

3-cyano-4-hydroxy-1-methyl-2-quinolone
3-chloro-4-hydroxy-1-methyl-2-quinolone
4-Hydroxy-1-methyl-2-quinolone-3-acetic acid
3,3'-methylenebis-4-hydroxy-1-methyl-2-quinolone
boron difluoride complex of 3-acetyl-4-hydroxy-1-methyl-2-quinolone
4-hydroxy-1-methyl-3-[(3-nitrophenyl)azo]-2-quinolone
N-methyl-1-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methyl]cyclopropan-1-amine
2-(3-Amino-2-methylthiolan-3-yl)-2-hydroxyacetic acid
1-Methyl-2-[2-(propan-2-yl)-1,3-thiazol-5-yl]pyrrolidin-3-amine
3-(2-Fluoroethyl)-1-(2-methoxyethyl)thiourea
(3S)-3-{[(benzyloxy)carbonyl]amino}-3-(4-bromo-1-methyl-1H-1,2,3-triazol-5-yl)propanoic acid
1-{N-methyl3-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxolane-2-amido}cyclobutane-1-carboxylic acid
2-(Cyclobutylmethyl)oxane-2-carbaldehyde
Methyl 2-[(but-3-yn-1-yl)(methyl)amino]pyridine-4-carboxylate
6-[(But-3-yn-1-yl)(methyl)amino]pyrimidine-4-carboxylic acid
Sodium 2-phenoxyethane-1-sulfinate

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