Flibanserin
Suppliers
Names
[ CAS No. ]:
167933-07-5
[ Name ]:
Flibanserin
[Synonym ]:
Ectris
1,3-Dihydro-1-(2-(4-(3-(trifluoromethyl)phenyl)-1-piperazinyl)ethyl)-2H-benzimidazol-2-one
Addyi
BIMT-17
Bimt 17
2H-Benzimidazol-2-one, 1,3-dihydro-1-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-
BIMT-17-BS
Flibanserin
3-[2-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]ethyl]-1H-benzimidazol-2-one
1-(2-(4-(3-trifluoromethylphenyl)piperazin-1-yl)ethyl)benzimidazol(1H)-2-one
1-(2-{4-[3-(Trifluoromethyl)phenyl]-1-piperazinyl}ethyl)-1,3-dihydro-2H-benzimidazol-2-one
1-(2-{4-[3-(Trifluoromethyl)phenyl]piperazin-1-yl}ethyl)-1,3-dihydro-2H-benzimidazol-2-one
Chemical & Physical Properties
[ Density]:
1.292 g/cm3
[ Molecular Formula ]:
C20H21F3N4O
[ Molecular Weight ]:
390.40200
[ Exact Mass ]:
390.16700
[ PSA ]:
44.27000
[ LogP ]:
3.17350
[ Appearance of Characters ]:
white to beige
[ Index of Refraction ]:
1.566
[ Storage condition ]:
2-8°C
[ Water Solubility ]:
DMSO: soluble10mg/mL, clear
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301-H315-H319-H335
[ Precautionary Statements ]:
P261-P301 + P310-P305 + P351 + P338
[ Hazard Codes ]:
T
[ Risk Phrases ]:
25-36/37/38
[ Safety Phrases ]:
26-45
[ RIDADR ]:
UN 2811 6.1 / PGIII
Articles
J. Sex. Med. 8(11) , 3160-72, (2011)
Flibanserin is a 5-HT(1A) agonist/5-HT(2A) antagonist that has been shown to increase sexual desire and reduce distress in premenopausal women with Hypoactive Sexual Desire Disorder (HSDD).To assess t...
J. Sex. Med. 9(12) , 3180-8, (2012)
Hypoactive Sexual Desire Disorder (HSDD) is a common form of Female Sexual Dysfunction characterized by low sexual desire that causes distress or interpersonal difficulty.This 52-week open-label exten...
J. Sex. Med. 8(12) , 3262-70, (2011)
Assessing the sexual response in women with female sexual dysfunctions (FSDs) in clinical trials remains difficult. Part of the challenge is the development of meaningful and valid end points that cap...