2-(4-methylpiperazin-1-yl)-1H-quinazolin-4-one

Names

[ CAS No. ]:
16822-65-4

[ Name ]:
2-(4-methylpiperazin-1-yl)-1H-quinazolin-4-one

[Synonym ]:
1p-333s
ami 098

Chemical & Physical Properties

[ Density]:
1.32g/cm3

[ Boiling Point ]:
395.4ºC at 760 mmHg

[ Molecular Formula ]:
C13H16N4O

[ Molecular Weight ]:
244.29200

[ Flash Point ]:
192.9ºC

[ Exact Mass ]:
244.13200

[ PSA ]:
52.49000

[ LogP ]:
1.09010

[ Vapour Pressure ]:
1.85E-06mmHg at 25°C

[ Index of Refraction ]:
1.68

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VA3832100
CHEMICAL NAME :
4(3H)-Quinazolinone, 2-(4-methyl-1-piperazinyl)-
CAS REGISTRY NUMBER :
16822-65-4
BEILSTEIN REFERENCE NO. :
1578887
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C13-H16-N4-O
MOLECULAR WEIGHT :
244.33
WISWESSER LINE NOTATION :
T66 BVM ENJ D- AT6N DNTJ D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Brain and Coverings - recordings from specific areas of CNS Behavioral - somnolence (general depressed activity) Behavioral - excitement
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 11,392,1968

Related Compounds

  • 7-chloro-2-(4-methylpiperazin-1-yl)-1H-quinazolin-4-one
  • 6-chloro-2-(4-methylpiperazin-1-yl)-1H-quinazolin-4-one
  • 2-[(4-methylpiperazin-1-yl)methyl]-1H-quinazolin-4-one
  • 2-(4-methylpiperazin-1-yl)-5,6,7,8-tetrahydro-1H-quinazolin-4-one
  • 2-(4-hydroxypiperidin-1-yl)-1H-quinazolin-4-one
  • 2-(4-benzylpiperazin-1-yl)-1H-quinazolin-4-one
  • 2-cyano-N-[(4-methylquinazolin-2-yl)methylcarbamoyl]acetamide
  • Tert-butyl 2-[2-(4-fluorophenyl)ethyl]piperazine-1-carboxylate
  • O-(2-phenylpropyl)hydroxylamine
  • Hydroxyamphetamine hydrochloride, (R)-
  • 1-Pentyl-1H-pyrazole-4-carbonitrile
  • tert-butyl N-[2-(N'-hydroxycarbamimidoyl)-2-methylethyl]carbamate
  • (1s)-1-(3-Bromo-5-fluorophenyl)ethan-1-amine
  • 1-(1-Methyl-1H-indol-3-yl)butan-2-amine
  • 2-Amino-3-(2-bromo-5-chlorophenyl)propanoic acid
  • 1-(3-Bromo-4-methoxybenzyl)cyclopropan-1-amine
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