(R)-N-[[3-[3-Fluoro-4-[4-morpholinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl]phthalimide

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Names

[ CAS No. ]:
168828-89-5

[ Name ]:
(R)-N-[[3-[3-Fluoro-4-[4-morpholinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl]phthalimide

[Synonym ]:
2-[[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]isoindole-1,3-dione
Linezolid Impurity 13

Chemical & Physical Properties

[ Density]:
1.441 g/cm3

[ Boiling Point ]:
619.13ºC at 760 mmHg

[ Melting Point ]:
205-207℃

[ Molecular Formula ]:
C22H20FN3O5

[ Molecular Weight ]:
425.41000

[ Flash Point ]:
328.238ºC

[ Exact Mass ]:
425.13900

[ PSA ]:
79.39000

[ LogP ]:
2.35160

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-[[(5R)-2-oxo-1,3-oxazolidin-5-yl]methyl]isoindole-1,3-dione
  • 4-(4-Bromo-2-fluorophenyl)morpholine
  • Potassium phthalimide
  • (R)-(3-(3-Fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl methanesulfonate
  • N-(3-Phthalimido-2-(R)-hydroxypropyl)-3-fluoro-4-(Morpholinyl)aniline
  • N,N-Carbonyldiimidazole
  • 3,4-Difluoronitrobenzene
  • 4-(2-Fluoro-4-nitrophenyl)morpholine
  • 3-Fluoro-4-morpholinoaniline

DownStream

  • Deacetyl Linezolid
  • Linezolid