N-(3-amino-4-ethoxyphenyl)acetamide

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Names

[ CAS No. ]:
17026-81-2

[ Name ]:
N-(3-amino-4-ethoxyphenyl)acetamide

[Synonym ]:
2-Ethoxy-5-acetylaminoaniline
3-Amino-4-ethoxyanilid kyseliny octove [Czech]
2-ethoxy-5-acetaminoaniline
Acetanilide,3-amino-4-ethoxy
p-Acetophenetidide,3'-amino
3-amino-4-ethoxyacetanilide
5-(Acetylamino)-2-ethoxyaniline
6-ethoxy-3-acetylaminoaniline
4-ethoxy-3-amino-acetanilide

Chemical & Physical Properties

[ Density]:
1.174g/cm3

[ Boiling Point ]:
411.5ºC at 760 mmHg

[ Molecular Formula ]:
C10H14N2O2

[ Molecular Weight ]:
194.23000

[ Flash Point ]:
202.7ºC

[ Exact Mass ]:
194.10600

[ PSA ]:
64.35000

[ LogP ]:
2.28010

[ Vapour Pressure ]:
5.55E-07mmHg at 25°C

[ Index of Refraction ]:
1.593

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AD8575000
CHEMICAL NAME :
Acetanilide, 3'-amino-4'-ethoxy-
CAS REGISTRY NUMBER :
17026-81-2
LAST UPDATED :
199701
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C10-H14-N2-O2
MOLECULAR WEIGHT :
194.26
WISWESSER LINE NOTATION :
2OR BZ DMV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
130 gm/kg/78W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Endocrine - thyroid tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
524 gm/kg/78W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Endocrine - thyroid tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
260 gm/kg/78W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Endocrine - thyroid tumors

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Escherichia coli
DOSE/DURATION :
333 ug/plate
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 7(Suppl 5),1,1985

Safety Information

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2,4-Dinitrochlorobenzene
  • N-(4-Ethoxy-3-nitrophenyl)acetamide
  • Phenacetin
  • N-(pivaloyloxy)phenacetin

DownStream

  • N-[3-(diethylamino)-4-ethoxyphenyl]acetamide

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • N-[3-[bis(2-hydroxyethyl)amino]-4-ethoxyphenyl]acetamide
  • N-[3-[(2-Cyanoethyl)(2-hydroxyethyl)amino]-4-ethoxyphenyl]acetamide
  • 4'-Ethoxy-3'-[N-ethyl-N-(2-cyanoethyl)amino]acetanilide
  • N-(3-amino-4-hydroxyphenyl)acetamide
  • N-(3-amino-4-butylphenyl)acetamide
  • N-(3-AMINO-4-METHOXYPHENETHYL)ACETAMIDE HYDROCHLORIDE