isonicotinic acid 2,2'-methylenedihydrazide

Names

[ CAS No. ]:
1707-15-9

[ Name ]:
isonicotinic acid 2,2'-methylenedihydrazide

[Synonym ]:
Methazide
Metazide
Isonicotinic acid 2,2'-methylenedihydrazide
Methazid
Bis(isonicotinylhydrazo)methane
Methazidum
Metazida [Spanish]
bis-(N'-isonicotinoyl-hydrazino)-methane
Metazidum [Latin]
Metazid
Methylenbis(isonicotinylhydrazid)
Bis-(N'-isonicotinoyl-hydrazino)-methan
N,N-Methylenebisisoniazid

Chemical & Physical Properties

[ Density]:
1.309g/cm3

[ Boiling Point ]:
451.8ºC at 760mmHg

[ Molecular Formula ]:
C13H14N6O2

[ Molecular Weight ]:
286.28900

[ Flash Point ]:
227.1ºC

[ Exact Mass ]:
286.11800

[ PSA ]:
108.04000

[ LogP ]:
1.16670

[ Vapour Pressure ]:
2.36E-08mmHg at 25°C

[ Index of Refraction ]:
1.616

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NS1987000
CHEMICAL NAME :
Isonicotinic acid, 2,2'-methylenedihydrazide
CAS REGISTRY NUMBER :
1707-15-9
BEILSTEIN REFERENCE NO. :
0294524
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C13-H14-N6-O2
MOLECULAR WEIGHT :
286.33

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3900 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 84,220,1953

Safety Information

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Isoniazid
  • Formaldehyde

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • isonicotinic acid 2,2'-methylenedihydrazide
  • Isonicotinic acid 2,2'-methylenedihydrazide
  • Isonicotinic acid,2,2'-[sulfonylbis(p-phenyleneiminocarbonylmethylene)]dihydrazide (8CI)
  • Isonicotinic acid, 2-acetamido-, 1-oxide (7CI)
  • isonicotinic acid-2-acetyl-3,5-dimethoxyphenyl ester
  • isonicotinic acid-(2,6-dimethyl-anilide)
  • N'-cycloheptyl-N-{2-[1-(2,5-dimethylbenzenesulfonyl)piperidin-2-yl]ethyl}ethanediamide
  • N-{2-[1-(2,5-dimethylbenzenesulfonyl)piperidin-2-yl]ethyl}-N'-(4-ethylphenyl)ethanediamide
  • N1-(2-(1-((2,5-dimethylphenyl)sulfonyl)piperidin-2-yl)ethyl)-N2-phenyloxalamide
  • N-{2-[1-(2,5-dimethylbenzenesulfonyl)piperidin-2-yl]ethyl}-N'-(2-phenylethyl)ethanediamide
  • N1-(2-(1-((2,5-dimethylphenyl)sulfonyl)piperidin-2-yl)ethyl)-N2-(2-methoxybenzyl)oxalamide
  • N1-(2-(1-((2,5-dimethylphenyl)sulfonyl)piperidin-2-yl)ethyl)-N2-methyloxalamide
  • N1-(2-(1-((2,5-dimethylphenyl)sulfonyl)piperidin-2-yl)ethyl)-N2-ethyloxalamide
  • N-{2-[1-(2,5-dimethylbenzenesulfonyl)piperidin-2-yl]ethyl}-N'-(2,3-dimethylphenyl)ethanediamide
  • N-{2-[1-(2,5-dimethylbenzenesulfonyl)piperidin-2-yl]ethyl}-N'-(2,6-dimethylphenyl)ethanediamide
  • N1-(2-(1-((2,5-dimethylphenyl)sulfonyl)piperidin-2-yl)ethyl)-N2-(2-methoxyphenyl)oxalamide