Nociceptin(Orphanin FQ)

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Names

[ CAS No. ]:
170713-75-4

[ Name ]:
Nociceptin(Orphanin FQ)

[Synonym ]:
Nociceptin
Orphanin FQ
L-Phenylalanylglycylglycyl-L-phenylalanyl-L-threonylglycyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-leucyl-L-alanyl-L-asparaginyl-L-glutamine
L-Glutamine,L-phenylalanylglycylglycyl-L-phenylalanyl-L-threonylglycyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-leucyl-L-alanyl-L-asparaginyl
L-Glutamine, L-phenylalanylglycylglycyl-L-phenylalanyl-L-threonylglycyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-leucyl-L-alanyl-L-asparaginyl-

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Molecular Formula ]:
C79H129N27O22

[ Molecular Weight ]:
1809.037

[ Exact Mass ]:
1807.980591

[ PSA ]:
831.40000

[ LogP ]:
-6.33

[ Index of Refraction ]:
1.657

[ Storage condition ]:
-20°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Pharmacological characterization of the nociceptin receptor, ORL1. Insight from the inward rectifier activation in the periaqueductal gray.

J. Biomed. Sci. 7 , 232, (2000)

A novel opioid receptor-like orphan receptor (ORL1) was cloned and identified to be homologous to classical opioid receptors but insensitive to traditional opioids. A heptadecapeptide, termed orphanin...

Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor.

Nature 377 , 532-535, (1995)

The ORL1 receptor, an orphan receptor whose human and murine complementary DNAs have recently been characterized, structurally resembles opioid receptors and is negatively coupled with adenylate cycla...

Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled receptor.

Science 270 , 792-794, (1995)

A heptadecapeptide was identified and purified from porcine brain tissue as a ligand for an orphan heterotrimeric GTP-binding protein (G protein)-coupled receptor (LC132) that is similar in sequence t...


More Articles


Related Compounds

  • nociceptin/orphanin FQ (16-17)
  • Nociceptin(1-7)(Orphanin FQ(1-7))
  • Orphanin FQ(1-11)
  • Nociceptin (1-13) amide trifluoroacetate salt
  • [Nphe1]Nociceptin(1-13)NH2 TFA
  • [(pF)Phe4]Nociceptin(1-13)NH2
  • 3-bromo-4-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)but-2-ynamido]benzoic acid
  • 3-Amino-3-(trifluoromethyl)pentanoic acid
  • Methyl[2-methyl-1-(5-methylpyridin-3-yl)propan-2-yl]amine
  • Methyl 5-(3-aminopropoxy)-2-hydroxybenzoate
  • 2-Oxo-3-(thian-3-yl)propanoic acid
  • 3,6-Bis(hexyloxy)naphthalene-2,7-dicarbaldehyde
  • Ethyl 2-amino-2-(5-bromopyrazin-2-yl)acetate
  • 1,1,1,3-Tetrafluoro-3-methylbutan-2-amine
  • (S)-(1-(2-Hydroxypropyl)-1H-pyrazol-3-yl)boronic acid
  • 2-(Azetidin-3-yloxy)-4-benzylmorpholine
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