2-(Trifluoromethyl)-4-pyridinol

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Names

[ CAS No. ]:
170886-13-2

[ Name ]:
2-(Trifluoromethyl)-4-pyridinol

[Synonym ]:
2-(Trifluoromethyl)-4-Hydroxypyridine
4-Pyridinol, 2-(trifluoromethyl)-
2-(Trifluoromethyl)-4-pyridinol
2-(trifluoromethyl)-1H-pyridin-4-one
2-(Trifluoromethyl)pyridin-4-ol

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
324.4±37.0 °C at 760 mmHg

[ Melting Point ]:
120.0 to 124.0 °C

[ Molecular Formula ]:
C6H4F3NO

[ Molecular Weight ]:
163.097

[ Flash Point ]:
150.0±26.5 °C

[ Exact Mass ]:
163.024506

[ PSA ]:
33.12000

[ LogP ]:
0.57

[ Appearance of Characters ]:
Powder | Off-white

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.457

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-(3-methylcyctopentyl)-2-piperazinone hydrochloride
  • dimethyl 5-(methyloxy)-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2,3-dicarboxylate
  • 5-(methyloxy)-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-carboxylic acid
  • dimethyl 5-(ethyloxy)-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2,3-dicarboxylate
  • 5-hydroxy-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-carboxylic acid
  • methyl 5-hydroxy-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-carboxylate
  • methyl 7-(trifluoromethyl)-5-{[(trifluoromethyl)sulfonyl]oxy}pyrazolo[1,5-a]pyridine-2-carboxylate
  • methyl 3-chloro-5-cyclopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-carboxylate
  • methyl 5-cyclopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-carboxylate

DownStream

  • 2-Trifluoromethyl-4-chloropyridine
  • 4-Ethoxy-2-(trifluoromethyl)pyridine
  • Ethyl 2-(trifluoromethyl)isonicotinate
  • 4-Methoxy-2-(trifluoromethyl)pyridine

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 5-Iodo-2-(trifluoromethyl)-4-pyridinol
  • 2-(Trifluoromethyl)-4-pyrimidinecarboxylic acid
  • 2-(trifluoromethyl)-4,5,6,7-tetrahydrothiazolo[4,5-c]pyridine
  • 2-(Trifluoromethyl)-4-[(trifluoromethyl)sulfanyl]aniline
  • 2-trifluoromethyl-4-fluoromandelic acid
  • 2-Chloro-5-(trifluoromethyl)-4-pyridinol
  • N-(5-{4-[4-(trifluoromethyl)pyrimidin-2-yl]piperazin-1-yl}pyridin-2-yl)cyclopropanecarboxamide
  • N-{5-[4-(5-ethylpyrimidin-2-yl)piperazin-1-yl]pyridin-2-yl}-2,2-dimethylpropanamide
  • 3-Cyclopropyl-1-(1-{5-methylpyrazolo[1,5-a]pyrimidin-7-yl}piperidin-4-yl)imidazolidine-2,4-dione
  • N-{5-[4-(4-methoxypyrimidin-2-yl)piperazin-1-yl]pyridin-2-yl}cyclopropanecarboxamide
  • 3-Phenyl-1-[1-(1,3,4-thiadiazol-2-yl)piperidin-4-yl]imidazolidine-2,4-dione
  • 1-(Azepan-1-yl)-2-(4-{pyrazolo[1,5-a]pyrimidin-5-yloxy}piperidin-1-yl)ethan-1-one
  • N-{5-[4-(6-ethyl-5-fluoropyrimidin-4-yl)piperazin-1-yl]pyridin-2-yl}-2,2-dimethylpropanamide
  • 7-{[1,3]thiazolo[4,5-c]pyridin-2-yl}-3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazine
  • 2,2-dimethyl-N-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]piperidin-3-yl}propanamide
  • 1-[(2-methyl-1,3-thiazol-4-yl)methyl]-4-[6-(1H-pyrazol-1-yl)pyridin-2-yl]piperazine
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