5-[(tert-butoxycarbonyl)amino]-2-chloroisonicotinic acid

Suppliers

Names

[ CAS No. ]:
171178-46-4

[ Name ]:
5-[(tert-butoxycarbonyl)amino]-2-chloroisonicotinic acid

[Synonym ]:
4-Pyridinecarboxylic acid, 2-chloro-5-[[(1,1-dimethylethoxy)carbonyl]amino]-
5-[N-(tert-butoxycarbonyl)amino]-2-chloropyridine-4-carboxylic acid
5-Amino-2-chloroisonicotinic acid,5-BOC protected
5-Boc-amino-2-chloropyridine-4-carboxylic acid
5-[(tert-butoxy)carbonylamino]-2-chloropyridine-4-carboxylic acid
2-Chloro-5-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)isonicotinic acid
5-((tert-butoxycarbonyl)amino)-2-chloroisonicotinic acid

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
420.6±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C11H13ClN2O4

[ Molecular Weight ]:
272.685

[ Flash Point ]:
208.2±28.7 °C

[ Exact Mass ]:
272.056396

[ PSA ]:
88.52000

[ LogP ]:
4.38

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.588

Safety Information

[ Risk Phrases ]:
20/21/22

[ Safety Phrases ]:
36/37-24/25

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Carbon dioxide
  • TERT-BUTYL (6-CHLOROPYRIDIN-3-YL)CARBAMATE
  • TMEDA
  • Diethyl ether
  • 6-Chloronicotinic acid
  • 5-Chloro-2-pyridinamine
  • Di-tert-butyl dicarbonate

DownStream

  • 5-Amino-2-chloroisonicotinic acid
  • 6-Chloropyrido[3,4-d]pyrimidin-4(3H)-one
  • methyl 2-chloro-5-[(2-methylpropan-2-yl)oxycarbonylamino]pyridine-4-carboxylate

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%