2H-1,24:12,15-Dietheno-6,10-metheno-16H-pyrido[2',3':17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinolin-22-ol,3,4,4a,5,16a,17,18,19-octahydro-9,21,26-trimethoxy-4,17-dimethyl-, (4aR,16aS)-(9CI)

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Names

[ CAS No. ]:
17132-74-0

[ Name ]:
2H-1,24:12,15-Dietheno-6,10-metheno-16H-pyrido[2',3':17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinolin-22-ol,3,4,4a,5,16a,17,18,19-octahydro-9,21,26-trimethoxy-4,17-dimethyl-, (4aR,16aS)-(9CI)

[Synonym ]:
Homothalicrine
N-methyl-daphnandrine
homaromoline
Thalrugosamine
homothalictrine
6,6',12'-trimethoxy-2,2'-dimethyl-oxyacanthan-7-ol
(+)-homoaromoline
Oxyacanthan-7-ol,6,6',12'-trimethoxy-2,2'-dimethyl

Chemical & Physical Properties

[ Density]:
1.204g/cm3

[ Boiling Point ]:
709.7ºC at 760mmHg

[ Molecular Formula ]:
C37H40N2O6

[ Molecular Weight ]:
608.72300

[ Flash Point ]:
383ºC

[ Exact Mass ]:
608.28900

[ PSA ]:
72.86000

[ LogP ]:
6.73520

[ Vapour Pressure ]:
8.25E-21mmHg at 25°C

[ Index of Refraction ]:
1.601

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MS9272000
CHEMICAL NAME :
Homoaromoline
CAS REGISTRY NUMBER :
17132-74-0
LAST UPDATED :
199206
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C37-H40-N2-O6

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
24500 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YHHPAL Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1953- Suspended 1966-78. Volume(issue)/page/year: 15,513,1980
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
6370 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YHHPAL Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1953- Suspended 1966-78. Volume(issue)/page/year: 15,513,1980

Precursor & DownStream

Precursor

  • 2H-1,24:12,15-Dietheno-6,10-metheno-16H-pyrido[2',3':17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinoline,3,4,4a,5,16a,17,18,19-octahydro-9,21,22,26-tetramethoxy-4,17-dimethyl-,(4aR,16aS)- (9CI)

DownStream

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)(4-(2-(furan-2-yl)-2-hydroxyethyl)piperazin-1-yl)methanone hydrochloride
  • N,5-dimethyl-N-(piperidin-2-ylmethyl)pyridin-2-amine hydrochloride
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine