Alexidine dihydrochloride

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Names

[ CAS No. ]:
1715-30-6

[ Name ]:
Alexidine dihydrochloride

[Synonym ]:
N,N''''-1,6-Hexanediylbis[N'-(2-ethylhexyl)(imidodicarbonimidic diamide)] dihydrochloride
n,n''''-hexane-1,6-diylbis[n'-(2-ethylhexyl)(imidodicarbonimidic diamide)] dihydrochloride
Alexidine dihydrochloride
Imidodicarbonimidic diamide, N,N''''-1,6-hexanediylbis[N'-(2-ethylhexyl)-, hydrochloride (1:2)
Bisguadine
Sterwin 904
UNII:I2A7616PY1
alexidine 2HCl
1,1'-Hexamethylene-bis(5-[2-ethylhexyl]biguanide)
QR-711
Bisguanidine
Compound-904

Chemical & Physical Properties

[ Density]:
1.1g/cm3

[ Boiling Point ]:
658.2ºC at 760mmHg

[ Melting Point ]:
220.6-223.4ºC

[ Molecular Formula ]:
C26H58Cl2N10

[ Molecular Weight ]:
581.712

[ Flash Point ]:
351.8ºC

[ Exact Mass ]:
580.422302

[ PSA ]:
167.58000

[ LogP ]:
8.60460

[ Vapour Pressure ]:
3.38E-17mmHg at 25°C

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ RIDADR ]:
NONH for all modes of transport

Articles

Chemical interaction of alexidine and sodium hypochlorite.

J. Endod. 38(1) , 112-6, (2012)

Recent studies have reported the color change and formation of precipitates containing para-chloroaniline (PCA) after a reaction of sodium hypochlorite (NaOCl) and chlorhexidine (CHX). Alexidine (ALX)...

Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy.

Nat. Commun. 6 , 6220, (2015)

The tumour microenvironment contributes to cancer metastasis and drug resistance. However, most high throughput screening (HTS) assays for drug discovery use cancer cells grown in monolayers. Here we ...

Pan-antimicrobial failure of alexidine as a contact lens disinfectant when heated in Bausch & Lomb plastic containers: implications for the worldwide Fusarium keratitis epidemic of 2004 to 2006.

Eye Contact Lens 38(4) , 222-6, (2012)

ReNu with MoistureLoc (ReNuML), containing the antimicrobial agent alexidine 0.00045%, was associated with the Fusarium keratitis epidemic of 2004 to 2006. Although a single-point source contamination...


More Articles

Related Compounds

  • Alexidine dihydrochloride
  • Alexidine-d10 Dihydrochloride
  • Benzylhydrazine dihydrochloride
  • Inolitazone (dihydrochloride)
  • Cefepime Dihydrochloride Monohydrate
  • Mirodenafil (dihydrochloride)
  • 5-(Chloromethyl)-3-methylpyrazolo[1,5-a]pyrimidin-7(4H)-one
  • (3aR,8aR)-N,N-Dicyclohexyl-2,2-dimethyl-4,4,8,8-tetraphenyltetrahydro-[1,3]dioxolo[4,5-e][1,3,2]dioxaphosphepin-6-amine
  • 1-(4-Chloro-2-fluoro-6-iodophenyl)ethan-1-one
  • 5-Methyl-1-((6aR,8R,9aS)-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-4-(1H-1,2,4-triazol-1-yl)pyrimidin-2(1H)-one
  • (S)-Methyl 3-amino-3-(3-methylpyridin-2-yl)propanoate
  • 7-Chloro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carbonitrile
  • Methyl 3-fluoro-3-phenylpentanoate
  • 6-Methoxy-3-(trifluoromethyl)quinoline
  • 7-Fluoro-1H-pyrazolo[3,4-c]pyridine
  • Methyl 2-amino-3-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)propanoate
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