1,1-Dichloro-1-fluoroethane

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Names

[ CAS No. ]:
1717-00-6

[ Name ]:
1,1-Dichloro-1-fluoroethane

[Synonym ]:
CFC 141b
R 141b
1,1-dichlorofluoroethane
F141b
HCFC 141b
Ethane, dichlorofluoro-
1,1-Dichloro-1-fluoroethane
Refrigerant 141b
HFA-141B
HCFC-141b
HFC141B
dichloro-1-fluoroethane
MFCD00042461
1-fluoro 1,1-dichloroethane
EINECS 404-080-1
1,1-Chloro-1-fluoroethane
Ethane, 1,1-dichloro-1-fluoro-
monofluorodichloroethane
GXGF1
DF-141b
Isotron 141b
cfc141b
Freon 141b
Solkane 141b
dichloromonofluoroethane
FC-141B

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
35.5±8.0 °C at 760 mmHg

[ Melting Point ]:
-104ºC

[ Molecular Formula ]:
C2H3Cl2F

[ Molecular Weight ]:
116.950

[ Flash Point ]:
-33.4±11.9 °C

[ Exact Mass ]:
115.959587

[ LogP ]:
1.75

[ Vapour Pressure ]:
521.9±0.1 mmHg at 25°C

[ Index of Refraction ]:
1.387

[ Stability ]:
Stable.

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KI0997000
CHEMICAL NAME :
Ethane, 1,1-dichloro-1-fluoro-
CAS REGISTRY NUMBER :
1717-00-6
BEILSTEIN REFERENCE NO. :
1731585
LAST UPDATED :
199806
DATA ITEMS CITED :
16
MOLECULAR FORMULA :
C2-H3-Cl2-F
MOLECULAR WEIGHT :
116.95

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
56700 ppm/6H
TOXIC EFFECTS :
Behavioral - tremor Behavioral - ataxia
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Liver - other changes
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
151 gm/m3/2H
TOXIC EFFECTS :
Behavioral - general anesthetic Behavioral - ataxia Lungs, Thorax, or Respiration - cyanosis
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
50 gm/m3/4H/4W-I
TOXIC EFFECTS :
Endocrine - evidence of thyroid hypofunction
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
18200 mg/m3/4H/26W-I
TOXIC EFFECTS :
Vascular - BP lowering not characterized in autonomic section Kidney, Ureter, Bladder - proteinuria Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
20000 ppm/6H/28D-I
TOXIC EFFECTS :
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
18200 mg/m3/4H/26W-I
TOXIC EFFECTS :
Blood - changes in leukocyte (WBC) count
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
DOSE :
20000 ppm/6H
SEX/DURATION :
female 6-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
DOSE :
20000 ppm/6H
SEX/DURATION :
female 6-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetal death

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
10 pph/4H (Continuous)
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 33,491,1995

Safety Information

[ Hazard Codes ]:
Xi: Irritant;N: Dangerous for the environment;

[ Risk Phrases ]:
R59

[ Safety Phrases ]:
23-36/37/39-61-59

[ RIDADR ]:
UN 9274

[ HS Code ]:
2903730000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • VINYLIDENE CHLORIDE
  • Tantalum(V) fluoride
  • 1,1,1-Trichloroethane
  • 1,1,2-Trichlorotrifluoroethane
  • HYDROFLUORIC ACID
  • Trifluorostibine
  • Dichloromethane
  • 1,1,3,3-Tetrachloro-1,3-difluoroacetone
  • Acetone
  • antimony(v) chloride

DownStream

  • 1,1,1-Trifluoroethane
  • f 142b
  • 1-chloro-1-fluoroethylene
  • VINYLIDENE CHLORIDE
  • acetic acid
  • fluoroethane
  • monochloroethane
  • 1-chloro-1-fluoroethane
  • 1,2-Dichloro-1,1-difluoroethane
  • Acetonitrile, 2-(triphenylstannyl)-

Customs

[ HS Code ]: 2903791014

[ Summary ]:
2903791014 1,1-dichloro-1-fluoroethane。supervision conditions:14xy。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:5.5%。general tariff:30.0%

Related Compounds

  • 1,1-dichloro-1-fluoroethane,hydrate
  • 1,1-dichloro-1-phenyl-1λ5-arsinane
  • 1,1-dichloro-1,2,2,3,3,3-hexafluoropropane
  • 1,1-dichloro-1-fluoro-2-nitropropane
  • 1,1-dichloro-1,3,3,4,4,5,5,5-octafluoropentan-2-one
  • 1,1-dichloro-1,3,3-trifluorobutane
  • 2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-iodobenzoic acid
  • 2-[6-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-9H-purin-9-yl]acetic acid
  • 2-[4-(methoxycarbonyl)-1-methyl-1H-pyrazol-5-yl]prop-2-enoic acid
  • 7-chloro-6-nitro-3,4-dihydro-2H-1-benzopyran
  • 3-ethyl-1-[5-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pentanoyl]piperidine-3-carboxylic acid
  • 1-[5-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpentanoyl]-4-methylpiperidine-2-carboxylic acid
  • 2-({[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)furan-2-yl]formamido}methyl)-3,3,3-trifluoropropanoic acid
  • 4-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpropanamido]-5-oxopyrrolidine-3-carboxylic acid
  • 1-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methoxypropanoyl]-1,2,3,6-tetrahydropyridine-4-carboxylic acid
  • 3-{1-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methoxypropanoyl]piperidin-4-yl}propanoic acid
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