20-α-DIHYDROCORTISOL

Names

[ CAS No. ]:
1719-79-5

[ Name ]:
20-α-DIHYDROCORTISOL

[Synonym ]:
REICHSTEIN'S EPI ''E''
20alpha-hydroxycortisol
REICHSTEIN'S SUBSTANCE 'EPI' 'E'
11B,17ALPHA,20ALPHA,21-Tetrahydroxy-4-pregnen-3-one
4-PREGNEN-11BETA,17ALPHA,20ALPHA,21-TETROL-3-ONE
4-pregnene-11B,17A,20A,21-tetrol-3-one

Chemical & Physical Properties

[ Density]:
1.29 g/cm3

[ Boiling Point ]:
586.6ºC at 760 mmHg

[ Molecular Formula ]:
C21H32O5

[ Molecular Weight ]:
364.47600

[ Flash Point ]:
322.6ºC

[ Exact Mass ]:
364.22500

[ PSA ]:
94.83000

[ LogP ]:
1.86150

[ Vapour Pressure ]:
3.34E-16mmHg at 25°C

[ Index of Refraction ]:
1.602

Synthetic Route

Precursor & DownStream

Precursor

  • Hydrocortisone
  • Pregn-4-en-3-one,21-(acetyloxy)-11,17,20-trihydroxy-, (11b,20S)-

DownStream


Related Compounds

  • Alkenes, C4-20 α-, γ-ω-perfluoro
  • Alkenes, C14-20 α-, chlorosulfurized
  • Alkenes, C15-20 α-, isomerized
  • Alkenes, C14-20 α-
  • 5-alpha-pregnane-3-beta,20-alpha-diol
  • methyl 18-β-acetoxy-10,17-α-dimethoxy-3-oxo-2,3-seco-20-α-yohimbane-16-β-carboxylate
  • 2-[3-(4-chlorophenyl)-6-oxopyridazin-1(6H)-yl]-N-[2-(1H-indol-3-yl)ethyl]acetamide
  • 7-hydroxy-3-(2-(4-(3-methoxyphenyl)piperazin-1-yl)-2-oxoethyl)-4,8-dimethyl-2H-chromen-2-one
  • 2-{2-[4-(4-methoxyphenyl)piperazino]-2-oxoethyl}-6-[4-(methylsulfanyl)phenyl]-3(2H)-pyridazinone
  • N-(3,4-dimethoxybenzyl)-2-(3-(furan-2-yl)-6-oxopyridazin-1(6H)-yl)acetamide
  • 2,3-dimethyl-5-oxo-N-[4-(1H-1,2,4-triazol-1-ylmethyl)phenyl]-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide
  • 2-[3-(2-fluoro-4-methoxyphenyl)-6-oxopyridazin-1(6H)-yl]-N-[(2Z)-3,4,5,6,7,8-hexahydro-2H-cyclohepta[d][1,3]thiazol-2-ylidene]acetamide
  • N-[2-(4-oxoquinazolin-3(4H)-yl)ethyl]biphenyl-4-carboxamide
  • N-(6-methylpyridin-2-yl)-2-(3-(naphthalen-2-yl)-6-oxopyridazin-1(6H)-yl)acetamide
  • N-(3,4-dimethoxybenzyl)-2-(3-oxo-3,5,6,7,8,9-hexahydro-2H-cyclohepta[c]pyridazin-2-yl)acetamide
  • ethyl 4-{[1-(1H-tetrazol-1-yl)cyclohexyl]carbonyl}piperazine-1-carboxylate
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