Imperatoxin A

[ Molecular Formula ]:
C₁₄₈H₂₆₀N₅₈O₄₅S₆

[ Molecular Weight ]:
3764.4

[ Appearance of Characters ]:
lyophilized powder

[ Storage condition ]:
−20°C

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H332

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
20/21/22

[ Safety Phrases ]:
7-9-36/37

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Scorpion toxins targeted against the sarcoplasmic reticulum Ca(2+)-release channel of skeletal and cardiac muscle.

Proc. Natl. Acad. Sci. U. S. A. 89 , 12185-12189, (1992)

We report the purification of two peptides, called "imperatoxin inhibitor" and "imperatoxin activator," from the venom of the scorpion Pandinus imperator targeted against ryanodine receptor Ca(2+)-rel...

Peptide probe of ryanodine receptor function. Imperatoxin A, a peptide from the venom of the scorpion Pandinus imperator, selectively activates skeletal-type ryanodine receptor isoforms.

J. Biol. Chem. 270 , 28696-28704, (1995)

We have used [3H]ryanodine binding experiments and single channel recordings to provide convergent descriptions of the effect of imperatoxin A (IpTxa), a approximately 5-kDa peptide from the venom of ...

Primary structure and synthesis of Imperatoxin A (IpTx(a)), a peptide activator of Ca2+ release channels/ryanodine receptors.

FEBS Lett. 405 , 385-389, (1997)

We present the complete amino acid sequence of Imperatoxin A (IpTx(a)), a 33-amino-acid peptide from the venom of the scorpion P. imperator which activates Ca2+ release channels/ryanodine receptors (R...

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