[2-(2-Amino-6-chloro-9H-purin-9-yl)ethyl]propanedioic acid dimethyl ester

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Names

[ CAS No. ]:
172529-93-0

[ Name ]:
[2-(2-Amino-6-chloro-9H-purin-9-yl)ethyl]propanedioic acid dimethyl ester

[Synonym ]:
dimethyl 2-[2-(2-amino-6-chloropurin-9-yl)ethyl]malonate
Dimethyl 2-(2-(2-amino-6-chloro-9H-purin-9-yl)ethyl)malonate
DIMETHYL [2-(2-AMINO-6-CHLORO-9H-PURIN-9-YL)ETHYL]MALONATE

Chemical & Physical Properties

[ Density]:
1.59

[ Boiling Point ]:
557.044ºC at 760 mmHg

[ Melting Point ]:
115-116ºC

[ Molecular Formula ]:
C12H14ClN5O4

[ Molecular Weight ]:
327.72400

[ Flash Point ]:
290.69ºC

[ Exact Mass ]:
327.07300

[ PSA ]:
122.22000

[ LogP ]:
0.99540

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.666

Safety Information

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • dimethyl 2-[2-(guanin-9-yl)ethyl]malonate
  • 2-[2-(guanin-9-yl)ethyl]malonic acid
  • Triethyl 3-bromopropane-1,1,1-tricarboxylate
  • Sodium Methylate
  • 2-Amino-6-chloropurine

DownStream

  • Penciclovir
  • 9-(4-Acetoxy-3-acetoxymethylbutyl)-2-amino-6-chloropurine
  • Famciclovir
  • 2-[2-(2-amino-6-chloropurin-9-yl)ethyl]propane-1,3-diol

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%