(1,4-dioxidoquinoxaline-2,3-diyl)dimethanol

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Names

[ CAS No. ]:
17311-31-8

[ Name ]:
(1,4-dioxidoquinoxaline-2,3-diyl)dimethanol

[Synonym ]:
Quinoxalinium, 1,4-dihydro-4-hydroxy-2,3-bis(hydroxymethyl)-1-oxo-, inner salt
2,3-Quinoxalinedimethanol 1,4-dioxide
2,3-dihydroxymethylquinoxaline 1,4-di-N-oxide
2,3-Bis(hydroxymethyl)-1-oxoquinoxalin-1-ium-4(1H)-olate
DIOXIDINE
Dioxidin
(1,4-dioxidoquinoxaline-2,3-diyl)dimethanol
Dioxydine
1,4-Di-N-oxide of dihydroxymethylquinoxaline

Chemical & Physical Properties

[ Density]:
1.5

[ Melting Point ]:
171-172ºC

[ Molecular Formula ]:
C10H10N2O4

[ Molecular Weight ]:
222.197

[ Exact Mass ]:
222.064056

[ PSA ]:
91.38000

[ LogP ]:
0.68140

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VD1900000
CHEMICAL NAME :
2,3-Quinoxalinedimethanol, 1,4-dioxide
CAS REGISTRY NUMBER :
17311-31-8
LAST UPDATED :
199803
DATA ITEMS CITED :
24
MOLECULAR FORMULA :
C10-H10-N2-O4
MOLECULAR WEIGHT :
222.22
WISWESSER LINE NOTATION :
T66 BN ENJ BO C1Q D1Q EO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
300 mg/kg
SEX/DURATION :
female 11 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetal death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
300 mg/kg
SEX/DURATION :
female 10 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
300 mg/kg
SEX/DURATION :
female 10 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetal death
TYPE OF TEST :
Sex chromosome loss and nondisjunction
TYPE OF TEST :
Dominant lethal test
TYPE OF TEST :
Cytogenetic analysis
TYPE OF TEST :
Cytogenetic analysis
TYPE OF TEST :
Cytogenetic analysis
TYPE OF TEST :
Dominant lethal test
TYPE OF TEST :
Dominant lethal test

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
270 mg/kg
REFERENCE :
SOGEBZ Soviet Genetics. English translation of GNKAA5. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.2- 1966- Volume(issue)/page/year: 14,640,1978

Safety Information

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Quinoxaline,2,3-bis(bromomethyl)-
  • 2,3-BIS(ACETOXYMETHYL)QUINOXALINE 1,4-DIOXIDE
  • Conoidin A

DownStream

  • 1,3-dihydrofuro[3,4-b]quinoxalin-3-ol
  • quinoxaline-2,3-dicarbaldehyde
  • DHQ
  • 3-(hydroxymethyl)-4-oxido-1H-quinoxalin-4-ium-2-one

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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