SQ22536

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Names

[ CAS No. ]:
17318-31-9

[ Name ]:
SQ22536

[Synonym ]:
9-(Tetrahydro-2-furanyl)-9H-purin-6-amine,9-THF-Ade
9H-Purin-6-amine, 9-(tetrahydro-2-furanyl)-
9-(oxolan-2-yl)purin-6-amine
9-(tetrahydrofuran-2-yl)-9h-purin-6-amine
9-(Tetrahydrofuryl)adenine
MFCD00210216
9-(Tetrahydro-2-furanyl)-9H-purin-6-amine
SQ 22536
SQ22536

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
474.8±55.0 °C at 760 mmHg

[ Melting Point ]:
160-161ºC

[ Molecular Formula ]:
C9H11N5O

[ Molecular Weight ]:
205.217

[ Flash Point ]:
241.0±31.5 °C

[ Exact Mass ]:
205.096359

[ PSA ]:
78.85000

[ LogP ]:
-0.17

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.831

Safety Information

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2934999090

Synthetic Route

Precursor & DownStream

Precursor

  • 9-(4-chlorobut-2-ynyl)purin-6-amine
  • 4-(6-aminopurin-9-yl)but-2-yn-1-ol
  • 6H-Purin-6-imine, 1,7-dihydro- (9CI)
  • 2,3-DHF
  • tetrahydro-2-furyl acetate

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Compartmentalization of distinct cAMP signaling pathways in mammalian sperm.

J. Biol. Chem. 288(49) , 35307-20, (2013)

Fertilization competence is acquired in the female tract in a process known as capacitation. Capacitation is needed for the activation of motility (e.g. hyperactivation) and to prepare the sperm for a...

Ibudilast, a mixed PDE3/4 inhibitor, causes a selective and nitric oxide/cGMP-independent relaxation of the intracranial vertebrobasilar artery.

Eur. J. Pharmacol. 650(2-3) , 605-11, (2011)

Ibudilast, a mixed phosphodiesterase (PDE) 3/4 inhibitor, is a cerebral vasodilator widely used in Japan for treating post-stroke dizziness. However, little studies have been conducted on the vasorela...

IL-6, A1 and A2aR: a crosstalk that modulates BDNF and induces neuroprotection.

Biochem. Biophys. Res. Commun. 449(4) , 477-82, (2014)

Several diseases are related to retinal ganglion cell death, such as glaucoma, diabetes and other retinopathies. Many studies have attempted to identify factors that could increase neuroprotection aft...


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Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 3-{2-[5-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pyridin-2-yl]acetamido}-2,2-difluoropropanoic acid
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide